Molecular structure of RSL3, CAS Number: 1219810-16-8
RSL3 (CAS 1219810-16-8)
CAS Number:
1219810-16-8
Molecular Weight:
440.88
Molecular Formula:
C23H21ClN2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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RSL3 (CAS 1219810-16-8) References
- RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer. | Sui, X., et al. 2018. Front Pharmacol. 9: 1371. PMID: 30524291
- NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells. | Gryzik, M., et al. 2021. Biochim Biophys Acta Mol Cell Res. 1868: 118913. PMID: 33245979
- Broadening horizons: the role of ferroptosis in cancer. | Chen, X., et al. 2021. Nat Rev Clin Oncol. 18: 280-296. PMID: 33514910
- Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression. | Cui, Y., et al. 2021. J Neuroinflammation. 18: 249. PMID: 34717678
- Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer. | Yang, J., et al. 2021. Cell Death Dis. 12: 1079. PMID: 34775496
- RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma. | Li, S., et al. 2021. Oxid Med Cell Longev. 2021: 2915019. PMID: 34987700
- Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutant colorectal cancer. | Chen, H., et al. 2022. Redox Biol. 55: 102426. PMID: 35963119
- RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis. | Li, M., et al. 2022. Biochim Biophys Acta Mol Basis Dis. 1868: 166529. PMID: 36041715
- PHKG2 regulates RSL3-induced ferroptosis in Helicobacter pylori related gastric cancer. | Zhu, W., et al. 2023. Arch Biochem Biophys. 740: 109560. PMID: 36948350
- Irreversible HER2 inhibitors overcome resistance to the RSL3 ferroptosis inducer in non-HER2 amplified luminal breast cancer. | Park, SY., et al. 2023. Cell Death Dis. 14: 532. PMID: 37596261
Inhibitor of:
α-defensin 6, GOT1L1, GPx-2, GPx-4, GPx-7, Selenoprotein M, SPTRX-3, and TXNDC14.Activator of:
caspase-1, Mel13, Nix, PRX II, SENP2, SMYD3, and Tim10.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RSL3, 10 mg | sc-507385 | 10 mg | $250.00 |