Molecular structure of (RS)-MSPG, CAS Number: 169209-64-7
(RS)-MSPG (CAS 169209-64-7)
Alternate Names:
(RS)-α-Methyl-4-sulphonophenylglycine
Application:
(RS)-MSPG is a non-selective antagonist of presynaptic mGluRs
CAS Number:
169209-64-7
Molecular Weight:
245.25
Molecular Formula:
C9H11NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(RS)-MSPG, or (RS)-alpha-methyl-4-sulphonophenylglycine, is a non-selective antagonist of metabotropic glutamate receptors (mGluR). (RS)-MSPG is employed with (RS)-MCPG (sc-202325) and other phenylglycine derivative mGluR antagonists to probe the activity of the mGluR system.
(RS)-MSPG (CAS 169209-64-7) References
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- N-acetylaspartylglutamate and beta-NAAG protect against injury induced by NMDA and hypoxia in primary spinal cord cultures. | Yourick, DL., et al. 2003. Brain Res. 991: 56-64. PMID: 14575876
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- Metabotropic glutamate receptors inhibit microglial glutamate release. | McMullan, SM., et al. 2012. ASN Neuro. 4: PMID: 22770428
- New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. | Jane, DE., et al. 1995. Neuropharmacology. 34: 851-6. PMID: 8532166
- Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. | Bushell, TJ., et al. 1996. Br J Pharmacol. 117: 1457-62. PMID: 8730739
- Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. | Bedingfield, JS., et al. 1996. Eur J Pharmacol. 309: 71-8. PMID: 8864696
Inhibitor of:
mGluR-4, mGluR-6, mGluR-7, and mGLuR-8.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(RS)-MSPG, 5 mg | sc-203247 | 5 mg | $48.00 | |||
(RS)-MSPG, 10 mg | sc-203247A | 10 mg | $201.00 |