Molecular structure of (RS)-4-Bromo-homo-ibotenic acid, CAS Number: 71366-32-0
(RS)-4-Bromo-homo-ibotenic acid (CAS 71366-32-0)
Application:
(RS)-4-Bromo-homo-ibotenic acid is a potent AMPA receptor agonist
CAS Number:
71366-32-0
Molecular Weight:
251.0
Molecular Formula:
C6H7N2O4Br
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(RS)-4-Bromo-homo-ibotenic acid is a potent AMPA receptor agonist. Selective but relatively non-potent group I mGluR agonist.
(RS)-4-Bromo-homo-ibotenic acid (CAS 71366-32-0) References
- Pharmacological agents acting at subtypes of metabotropic glutamate receptors. | Schoepp, DD., et al. 1999. Neuropharmacology. 38: 1431-76. PMID: 10530808
- Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. | Watkins, JC., et al. 1990. Trends Pharmacol Sci. 11: 25-33. PMID: 2155495
- Excitatory amino acid agonists. Enzymic resolution, X-ray structure, and enantioselective activities of (R)- and (S)-bromohomoibotenic acid. | Hansen, JJ., et al. 1989. J Med Chem. 32: 2254-60. PMID: 2552114
- Effects of bromohomoibotenate on metabotropic glutamate receptors. | Thomsen, C., et al. 1994. Neuroreport. 5: 2417-20. PMID: 7696571
- 4-Bromohomoibotenic acid selectively activates a 1-aminocyclopentane-1S,3R-dicarboxylic acid-insensitive metabotropic glutamate receptor coupled to phosphoinositide hydrolysis in rat cortical slices. | Chung, DS., et al. 1994. J Neurochem. 63: 133-9. PMID: 8207423
- 4-Methylhomoibotenic acid activates a novel metabotropic glutamate receptor coupled to phosphoinositide hydrolysis. | Chung, DS., et al. 1997. J Pharmacol Exp Ther. 283: 742-9. PMID: 9353394
Activator of:
GluR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(RS)-4-Bromo-homo-ibotenic acid, 5 mg | sc-203244 | 5 mg | $200.00 |