Molecular structure of RS 127445 hydrochloride, CAS Number: 199864-87-4
RS 127445 hydrochloride (CAS 199864-87-4)
Application:
RS 127445 hydrochloride is a high affinity SR-2B antagonist
CAS Number:
199864-87-4
Molecular Weight:
317.79
Molecular Formula:
C17H16FN3 HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
High affinity 5-HT2B receptor antagonist (pKi = 9.5). Displays 1000-fold selectivity for 5-HT2B with good bioavailability.
RS 127445 hydrochloride (CAS 199864-87-4) References
Bonhaus et al (1999) RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist. Br.J.Pharmacol. 127 1075. Callebert et al (2006) Evidence for a control of plasma serotonin levels by 5-Hydroxytryptamine2B receptors in mice. J.Pharmacol.Exp.Ther. 317 724.Inhibitor of:
SR-2B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RS 127445 hydrochloride, 10 mg | sc-204244 | 10 mg | $127.00 | |||
RS 127445 hydrochloride, 50 mg | sc-204244A | 50 mg | $650.00 |