Date published: 2025-12-3

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RR-SRC, Protein Tyrosine Kinase Substrate (CAS 81156-93-6)

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Alternate Names:
Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly
Application:
RR-SRC, Protein Tyrosine Kinase Substrate is a tyrosine kinase substrate used to measure the activity of tyrosine kinases
CAS Number:
81156-93-6
Molecular Weight:
1519.66
Molecular Formula:
C64H106N22O21
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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RR-SRC is a tyrosine kinase substrate. RR-SRC has commonly been used to ascertain the activity of tyrosine kinases by measuinrg the phosphorylation of RR-SRC in both plant and animal cells. The substarte has also been used to monitor the purification of the insulin receptor, a protein tyrosine kinase. Tyrosine phosphorylation of RR-SRC is stimulated in vitro by EGF (epidermal growth factor).


RR-SRC, Protein Tyrosine Kinase Substrate (CAS 81156-93-6) References

  1. Protein tyrosine kinase-dependent release of intracellular calcium in the sea urchin egg.  |  Shen, SS., et al. 1999. Dev Growth Differ. 41: 345-55. PMID: 10400396
  2. Characterization of affinity-purified insulin receptor/kinase. Effects of dithiothreitol on receptor/kinase function.  |  Pike, LJ., et al. 1986. J Biol Chem. 261: 3782-9. PMID: 3005300
  3. Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.  |  Pike, LJ., et al. 1982. Proc Natl Acad Sci U S A. 79: 1443-7. PMID: 6175968
  4. Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell line.  |  Casnellie, JE., et al. 1982. Proc Natl Acad Sci U S A. 79: 282-6. PMID: 6804939
  5. Evidence of protein-tyrosine kinase activity in Catharanthus roseus roots transformed by Agrobacterium rhizogenes.  |  Rodríguez-Zapata, LC. and Hernández-Sotomayor, SM. 1998. Planta. 204: 70-7. PMID: 9443385
  6. Effects of tyrosine kinase inhibitor on the motility and ATP concentrations of fowl spermatozoa.  |  Ashizawa, K., et al. 1998. Mol Reprod Dev. 49: 196-202. PMID: 9444662
  7. Protein phosphorylation during coconut zygotic embryo development.  |  Islas-Flores, I., et al. 1998. Plant Physiol. 118: 257-63. PMID: 9733545

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

RR-SRC, Protein Tyrosine Kinase Substrate, 1 mg

sc-201166
1 mg
$100.00