RPMI2650 Whole Cell Lysate: sc-364192
- 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
- human whole cell lysate; epithelioid carcinoma cells
- whole cell lysate provided as Western blotting positive control
- should be stored at -20°C and repeated freezing and thawing should be minimized
- sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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RPMI2650 whole cell lysate is derived from the RPMI2650 cell line, a human nasal septum carcinoma line used extensively in respiratory epithelial research. This lysate is pivotal for exploring the cellular mechanisms related to nasal epithelial cell function and carcinoma characteristics. It provides a rich source for studying epithelial-mesenchymal transition (EMT), a process critical in the progression and metastasis of carcinoma cells. Researchers use RPMI2650 lysate to analyze the expression and regulatory mechanisms of key genes involved in EMT, including those coding for various cytokines, growth factors, and matrix metalloproteinsases (MMPs). This lysate also facilitates investigation into the pathways that regulate cell adhesion and migration, critical aspects in the study of carcinoma cell invasion. Furthermore, RPMI2650 lysate is used to examine how environmental factors, such as pollutants and toxins, affect the respiratory epithelium at the molecular level, particularly focusing on cellular stress responses and alterations in gene expression. Through these applications, RPMI2650 cell lysate contributes significantly to advancing the understanding of nasal epithelial biology and carcinoma.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RPMI2650 Whole Cell Lysate | sc-364192 | 500 µg/200 µl | $118.00 |