Rpb11 Antibody (4Y11): sc-58005
- Rpb11 Antibody (4Y11) is a mouse monoclonal IgG1 Rpb11 antibody provided at 100 µl ascites
- raised against recombinant full length Rpb11 of yeast origin
- recommended for detection of Rpb11 of S. cerevisiae origin by WB and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rpb11 Antibody (4Y11). This work is in progress.
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Rpb11 Antibody (4Y11) is a mouse monoclonal IgG1 antibody that detects Rpb11 protein of S. cerevisiae origin by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). anti-Rpb11 antibody (4Y11) is available as the non-conjugated isotype antibody. Rpb11 protein plays a crucial role in transcription, as a vital component of eukaryotic RNA polymerase II, responsible for synthesizing messenger RNA from DNA templates. This function is essential for gene expression regulation, particularly in response to environmental stress, where organisms must adapt transcriptional profiles to survive. Rpb11 subunit is encoded by RPB11 gene, located on chromosome XV, and relates closely to AC19 subunit found in RNA polymerases I and III, highlighting importance in transcription machinery across different polymerases. Rpb11 protein consists of 120 amino acids and shares structural similarities with other RNA polymerase subunits, suggesting conserved mechanisms of action in transcription regulation. Using anti-Rpb11 antibody (4Y11) in experiments can provide insights into RNA polymerase II activity dynamics and implications in cellular responses to various stimuli.
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Rpb11 Antibody (4Y11) References:
- Dissociable Rpb4-Rpb7 subassembly of rna polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation. | Orlicky, SM., et al. 2001. J Biol Chem. 276: 10097-102. PMID: 11087726
- Rpb4, a non-essential subunit of core RNA polymerase II of Saccharomyces cerevisiae is important for activated transcription of a subset of genes. | Pillai, B., et al. 2001. J Biol Chem. 276: 30641-7. PMID: 11382749
- A human RNA polymerase II subunit is encoded by a recently generated multigene family. | Grandemange, S., et al. 2001. BMC Mol Biol. 2: 14. PMID: 11747469
- RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. | Woychik, NA. and Young, RA. 1989. Mol Cell Biol. 9: 2854-9. PMID: 2674672
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rpb11 Antibody (4Y11) | sc-58005 | 100 µl ascites | $333.00 |