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RPA 32 kDa subunit Antibody (B-4) is a mouse monoclonal IgG2b antibody that detects RPA 32 kDa subunit in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RPA 32 kDa subunit is a critical component of the heterotrimeric replication protein A complex, which plays a vital role in DNA replication, recombination, and repair processes. RPA 32 kDa subunit is primarily located in the nucleus, where RPA 32 kDa subunit binds to single-stranded DNA, facilitating the stabilization of DNA during replication and repair. RPA 32′s ability to interact with various DNA repair enzymes, such as UNG2, XPA, and Rad52, underscores RPA 32′s importance in maintaining genomic integrity. Additionally, RPA 32 kDa subunit is involved in telomere maintenance, which is crucial for cellular aging and stability. RPA 32′s interaction with the SH2 domain of Stat3 highlights RPA 32′s role in signaling pathways, where overexpression can enhance growth factor-stimulated tyrosine phosphorylation and transcriptional activity, further emphasizing RPA 32′s significance in cellular processes. Anti-RPA 32 kDa subunit antibody (B-4) is an essential tool for researchers studying DNA repair mechanisms and related signaling pathways in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RPA 32 kDa subunit Antibody (B-4) | sc-271578 | 200 µg/ml | $322.00 | |||
RPA 32 kDa subunit Antibody (B-4): m-IgG2b BP-HRP Bundle | sc-548542 | 200 µg Ab; 10 µg BP | $361.00 | |||
RPA 32 kDa subunit Antibody (B-4) X | sc-271578 X | 200 µg/0.1 ml | $322.00 |