Molecular structure of Rp-8-CPT-cAMPS, CAS Number: 129735-01-9
Rp-8-CPT-cAMPS (CAS 129735-01-9)
See product citations (2)
Alternate Names:
8-(4-Chlorophenylthio)adenosine-3′,5′-cyclic Monophosphorothioate, Rp-isomer sodium salt
Application:
Rp-8-CPT-cAMPS is a lipophillic analog of a competitive inhibitor of PKA
CAS Number:
129735-01-9
Purity:
≥99%
Molecular Weight:
509.86
Molecular Formula:
C16H14ClN5O5PS2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Rp-8-CPT-cAMPS is a lipophilic analog of the competitive inhibitor of protein kinase A (cyclic AMP antagonist).
Rp-8-CPT-cAMPS (CAS 129735-01-9) References
- Inhibition by adenosine receptor agonists of synaptic transmission in rat periaqueductal grey neurons. | Bagley, EE., et al. 1999. J Physiol. 516 (Pt 1): 219-25. PMID: 10066936
- Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase. | Spicuzza, L., et al. 2001. Br J Pharmacol. 133: 1201-12. PMID: 11498504
- Acute hypoxia induces vasodilation and increases coronary blood flow by activating inward rectifier K(+) channels. | Park, WS., et al. 2007. Pflugers Arch. 454: 1023-30. PMID: 17486361
- Multiple signals regulate phospholipase CBeta3 in human myometrial cells. | Zhong, M., et al. 2008. Biol Reprod. 78: 1007-17. PMID: 18322273
- PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells. | Roscioni, SS., et al. 2009. Respir Res. 10: 88. PMID: 19788733
- 8-pCPT-conjugated cyclic AMP analogs exert thromboxane receptor antagonistic properties. | Sand, C., et al. 2010. Thromb Haemost. 103: 662-78. PMID: 20135060
- Modulation of carbachol-induced Ca2+ oscillations in airway smooth muscle cells by PGE2. | Morgan, LM., et al. 2022. Cell Calcium. 103: 102547. PMID: 35134593
- Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP. | Weisskopf, MG., et al. 1994. Science. 265: 1878-82. PMID: 7916482
- Stimulation of renin secretion by NO donors is related to the cAMP pathway. | Kurtz, A., et al. 1998. Am J Physiol. 274: F709-17. PMID: 9575895
- The role of cAMP in the frequency-dependent changes in contraction of guinea-pig cardiomyocytes. | Money-Kyrle, AR., et al. 1998. Cardiovasc Res. 37: 532-40. PMID: 9614507
Inhibitor of:
AKAP 14, PKA, PKA IIα reg, PKAα cat, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rp-8-CPT-cAMPS, 5 µmol | sc-215821 | 5 µmol | $712.00 |