Roxithromycin (CAS 80214-83-1)
QUICK LINKS
Roxithromycin is a compound utilized in the field of microbiology, specifically to study macrolide antibiotic action mechanisms against a variety of bacterial species. It is frequently employed in research to analyze the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, which can elucidate the pathways of bacterial growth inhibition. The compound is also used in investigations of bacterial resistance mechanisms, helping researchers understand how certain bacteria evade the effects of macrolides and develop strategies to counteract resistance. In ecological studies, Roxithromycin is examined for its persistence and effects in aquatic environments, contributing to assessments of the impact of antibiotics on non-target organisms. Additionally, this compound is of interest in analytical chemistry research, where methods are developed and refined for detecting and quantifying antibiotic residues in food products and environmental samples.
Roxithromycin (CAS 80214-83-1) References
- Roxithromycin vs cefaclor. | Hughes, T., et al. 1993. Pharmacoeconomics. 4: 396-8. PMID: 10146876
- Roxithromycin-induced eosinophilic pneumonia. | Pérez-Castrillón, JL., et al. 2002. Ann Pharmacother. 36: 1808-9. PMID: 12398581
- Roxithromycin. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. | Young, RA., et al. 1989. Drugs. 37: 8-41. PMID: 2651088
- Pharmacokinetics of roxithromycin in paediatrics. | Bégué, P., et al. 1987. J Antimicrob Chemother. 20 Suppl B: 101-6. PMID: 3323162
- Pharmacokinetics of roxithromycin in renal and hepatic failure and drug interactions. | Periti, P. and Mazzei, T. 1987. J Antimicrob Chemother. 20 Suppl B: 107-12. PMID: 3323163
- Tissue distribution of roxithromycin. | Bergogne-Bérézin, E. 1987. J Antimicrob Chemother. 20 Suppl B: 113-20. PMID: 3323164
- Roxithromycin, a new macrolide antibiotic, in the treatment of infections in the lower respiratory tract: an overview. | Gentry, LO. 1987. J Antimicrob Chemother. 20 Suppl B: 145-52. PMID: 3323166
- Roxithromycin: a pharmacokinetic review of a macrolide. | Puri, SK. and Lassman, HB. 1987. J Antimicrob Chemother. 20 Suppl B: 89-100. PMID: 3323171
- Preparation and characterization of DNA aptamers against roxithromycin. | Jiang, L., et al. 2021. Anal Chim Acta. 1164: 338509. PMID: 33992220
- Roxithromycin. An update of its antimicrobial activity, pharmacokinetic properties and therapeutic use. | Markham, A. and Faulds, D. 1994. Drugs. 48: 297-326. PMID: 7527329
- Roxithromycin-induced digoxin toxicity. | Corallo, CE. and Rogers, IR. 1996. Med J Aust. 165: 433-4. PMID: 8913245
- Roxithromycin: review of its antimicrobial activity. | Bryskier, A. 1998. J Antimicrob Chemother. 41 Suppl B: 1-21. PMID: 9579708
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Roxithromycin, 1 g | sc-205845 | 1 g | $51.00 | |||
Roxithromycin, 5 g | sc-205845A | 5 g | $153.00 |