Rotigotine Hydrochloride CAS: 125572-93-2
MF: C19H25NOS•HCl
MW: 351.93
A D2DR and D3DR agonist.

Rotigotine Hydrochloride (CAS 125572-93-2)

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Application: Rotigotine Hydrochloride is a D2DR and D3DR agonist
CAS Number: 125572-93-2
Purity: ≥99%
Molecular Weight: 351.93
Molecular Formula: C19H25NOS•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Rotigotine Hydrochloride is a Dopamine D2DR and D3DR agonist (Ki values are 13 and 0.71 nM for D2DR and D3DR respectively) as well as a significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine Hydrochloride has shown antiparkinsonian activity.


References

Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989), Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997), Ferreira, J., et al.: Lancet, 355, 1333 (2000), Arnulf, I., et al.: Neurology, 58, 1019 (2002), Wisor, J., et al.: Neuroscience, 132, 1027 (2005),

Physical State :
Solid
Solubility :
Soluble in Acetone and DMSO
Storage :
Store at -20° C
Melting Point :
114-117°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
180335
SMILES :
CCCN(CCC1=CC=CS1)[[email protected]]1CCC2=C(O)C=CC=C2C1

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical, Rotigotine Hydrochloride: sc-212790, has a white to off-white powder appearance.
Answered by: Chemical Support 3
Date published: 2017-01-31
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