Date published: 2026-5-17

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Rosiglitazone Maleate (CAS 155141-29-0)

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Application:
Rosiglitazone Maleate is an insulin sensitizer shown to bind to PPAR&gamma
CAS Number:
155141-29-0
Purity:
≥99%
Molecular Weight:
473.504
Molecular Formula:
C18H19N3O3S•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Rosiglitazone Maleate is utilized in metabolic, in studies that explore cellular mechanisms of insulin sensitivity and glucose uptake. Rosiglitazone Maleate is important for understanding the biochemical pathways involved in glucose metabolism and energy balance within cells. Some may use Rosiglitazone Maleate to investigate its effects on adipocyte differentiation and function, which has implications for understanding metabolic disorders at a cellular level. The compound′s role in modulating lipid profiles and metabolic pathways also makes it useful for studies aimed at deciphering the complex interactions within metabolic syndromes. Rosiglitazone Maleate focusing on its impact on gene expression related to glucose and lipid metabolism, providing insights into the genetic factors that influence metabolic.


Rosiglitazone Maleate (CAS 155141-29-0) References

  1. Development and validation of spectrophotometric and HPTLC methods for simultaneous determination of rosiglitazone maleate and metformin hydrochloride in the presence of interfering matrix excipients.  |  Mahgoub, H., et al. 2014. Drug Dev Ind Pharm. 40: 1190-8. PMID: 23829222
  2. Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRα from Drugbank database.  |  Xu, D., et al. 2017. Bioorg Med Chem Lett. 27: 1055-1061. PMID: 28089347
  3. Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis: A Meta-analysis.  |  Musso, G., et al. 2017. JAMA Intern Med. 177: 633-640. PMID: 28241279
  4. Camel Milk Has Beneficial Effects on Diabetes Mellitus: A Systematic Review.  |  Mirmiran, P., et al. 2017. Int J Endocrinol Metab. 15: e42150. PMID: 29026408
  5. Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930.  |  Shinozuka, T., et al. 2019. ACS Med Chem Lett. 10: 358-362. PMID: 30891140
  6. A Cost Effective (QbD) Approach in the Development and Optimization of Rosiglitazone Maleate Mucoadhesive Extended Release Tablets -In Vitro and Ex Vivo.  |  Chappidi, SR., et al. 2019. Adv Pharm Bull. 9: 281-288. PMID: 31380254
  7. Auditory and Vestibular Side Effects of FDA-Approved Drugs for Diabetes.  |  DiSogra, RM. and Meece, J. 2019. Semin Hear. 40: 315-326. PMID: 31602095
  8. A Sensitive HPTLC Method for the Estimation of Glibenclamide, Rosiglitazone Maleate and Metformin Hydrochloride from a Multicomponent Dosage Form.  |  Bhende, SD., et al. 2020. J Chromatogr Sci. 58: 418-426. PMID: 32086517
  9. Cognitive Decline in Alzheimer's Disease: Limited Clinical Utility for GWAS or Polygenic Risk Scores in a Clinical Trial Setting.  |  Euesden, J., et al. 2020. Genes (Basel). 11: PMID: 32370229
  10. Early-Phase Interventional Trials in Oral Cancer Prevention.  |  McCarthy, C., et al. 2021. Cancers (Basel). 13: PMID: 34359746
  11. Down-Regulated miR-130a/b Attenuates Rhabdomyosarcoma Proliferation via PPARG.  |  Pan, Y., et al. 2021. Front Mol Biosci. 8: 766887. PMID: 35187064
  12. Efficacy and safety of hypoglycemic drugs in improving cognitive function in patients with Alzheimer's disease and mild cognitive impairment: A systematic review and network meta-analysis.  |  Wang, XC., et al. 2022. Front Neurol. 13: 1018027. PMID: 36530613
  13. Superporous acrylic acid and HPMC hydrogels of mefenamic acid: Formulation, characterization and optimization by central composite design.  |  Khan, HU., et al. 2022. Front Bioeng Biotechnol. 10: 1057627. PMID: 36588944

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rosiglitazone Maleate, 20 mg

sc-280069
20 mg
$166.00