rosiglitazone hydrochloride CAS: 302543-62-0
MF: C18H19N3O3S•HCl
MW: 393.893
An activator of PPARγ and an insulin sensitizer.

rosiglitazone hydrochloride (CAS 302543-62-0)

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Application: An activator of PPARγ and an insulin sensitizer
CAS Number: 302543-62-0
Molecular Weight: 393.893
Molecular Formula: C18H19N3O3S•HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Rosiglitazone hydrochloride is a potent, selective PPARγ (Peroxisome proliferator-activated receptor) agonist (Kd= 43 nM) which exhibits anti-diabetic and hepatoxic effects. PPARγ belongs to a group of nuclear receptor proteins that are essential to the regulation of cellular differentiation, development and metabolism, and plays a functional role in adipogenesis. Rosiglitazone, also known as BRL 49653, is a thiazolidinedione derivative effective in increasing insulin sensitivity in muscle and adipose tissue, as well as inducing adipocyte differentiation in pluripotent C3H10T1/2 stem cells.

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 3077, Class 9, Packing group III

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Certificate of Analysis

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