Date published: 2025-10-15

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ROS 234 dioxalate (CAS 184576-87-2)

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Alternate Names:
N-[3-(1H-Imidazol-4-yl)propyl]-1H-benzimidazol-2-amine dioxalate
Application:
ROS 234 dioxalate is A potent H3 antagonist
CAS Number:
184576-87-2
Molecular Weight:
421.37
Molecular Formula:
C17H19N5O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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ROS 234 dioxalate is a potent H3 antagonist (pKB = 9.46 at guinea-pig ileum H3 receptors). This compound shows limited blood brain barrier permeability.


ROS 234 dioxalate (CAS 184576-87-2) References

Ballabeni et al (2002) CNS access of selected H3-antagonists: ex vivo binding study in rats. Inflamm.Res. 51 Suppl.1 S55. Mor et al (2004) Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists. Bioorg.Med.Chem.Lett. 12 663.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ROS 234 dioxalate, 10 mg

sc-204893
10 mg
$140.00

ROS 234 dioxalate, 50 mg

sc-204893A
50 mg
$585.00