Ron α Antibody (29): sc-136060
- Ron α Antibody (29) is a mouse monoclonal IgG2b provided at 50 µg/0.5 ml
- raised against amino acids 40-224 of Ron α of human origin
- recommended for detection of Ron α of mouse, rat, human and canine origin by WB, IP and IF; not recommended for IP
- See Ron α (C-5): sc-393523 for Ron α antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ron α Antibody (29). This work is in progress.
Ron α Antibody (29) is a mouse monoclonal IgG2b antibody engineered to recognize amino acids 40-224 of the human Ron α precursor, also known as MST1R, macrophage-stimulating protein receptor (MSP receptor), or CD136 antigen. Ron α is the extracellular alpha chain of the Ron receptor tyrosine kinase, which plays a critical role in cellular communication by binding to its ligand, macrophage-stimulating protein (MSP). The structure of Ron α is characterized by a cysteine-rich extracellular domain that facilitates ligand binding and receptor dimerization, essential for activating downstream signaling pathways involved in cell growth, survival, and migration. This structural integrity is crucial as it ensures precise regulation of cellular responses to environmental stimuli, maintaining normal cellular homeostasis. The Ron receptor, comprising both Ron α and the transmembrane Ron β subunit, forms a disulfide-linked heterodimer that is pivotal for effective signal transduction. Ron α monoclonal antibody (29) is validated for use in western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications, demonstrating strong reactivity with Ron α from mouse, rat, human, and canine origins. However, anti-Ron α antibody (29) is not recommended for immunoprecipitation (IP), ensuring optimal performance in other applications. By targeting a specific and conserved epitope within the Ron α subunit, Ron α (29) antibody facilitates detailed studies of Ron-mediated signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ron α Antibody (29) | sc-136060 | 50 µg/0.5 ml | $322.00 |