Molecular structure of RO 19-4603, CAS Number: 99632-94-7
RO 19-4603 (CAS 99632-94-7)
Application:
RO 19-4603 is an agent that binds with high affinity to GABAA receptors
CAS Number:
99632-94-7
Molecular Weight:
319.38
Molecular Formula:
C15H17N3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
RO 19-4603 is a benzodiazepine inverse agonist. Antagonizes effects of ethanol on locomotor behavior and suppresses ethanol intake in alcohol-preferring rats. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors (Ki values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively).
RO 19-4603 (CAS 99632-94-7) References
1. Wong, G. and Skolnick, P. 1992. Eur. J. Pharmacol. 225: 63-68.2. June, H.L., et al. 1995. J. Pharmacol. Exp. Ther. 274: 1105-1112.
3. June, H.L., et al. 1998. Brain Res. 784: 256-275.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RO 19-4603, 10 mg | sc-203684 | 10 mg | $125.00 | |||
RO 19-4603, 50 mg | sc-203684A | 50 mg | $560.00 |