Molecular structure of Rizatriptan Benzoate, CAS Number: 145202-66-0
Rizatriptan Benzoate (CAS 145202-66-0)
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Alternate Names:
N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine Benzoate
Application:
Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist
CAS Number:
145202-66-0
Molecular Weight:
391.47
Molecular Formula:
C22H25N5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine. Rizatriptan Benzoate is an activator of SR-1B. Acting as a selective serotonin receptor agonist, it functions by constricting the blood vessels surrounding the brain and decreasing the release of specific substances that contribute to inflammation and pain.
Rizatriptan Benzoate (CAS 145202-66-0) References
- Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. | Keny, RV., et al. 2010. Indian J Pharm Sci. 72: 79-85. PMID: 20582194
- Development and Validation of HPTLC Method for the Estimation of Rizatriptan Benzoate in Bulk and Tablets. | Sundar, BS. and Suneetha, A. 2010. Indian J Pharm Sci. 72: 798-801. PMID: 21969758
- Development and evaluation of tamarind seed xyloglucan-based mucoadhesive buccal films of rizatriptan benzoate. | Avachat, AM., et al. 2013. Carbohydr Polym. 91: 537-42. PMID: 23121942
- Rizatriptan benzoate influences the endogenous pain modulatory system in a rat model of migraine. | Yao, G., et al. 2012. Neural Regen Res. 7: 131-5. PMID: 25767488
- Formulation of rizatriptan benzoate fast dissolving buccal films by emulsion evaporation technique. | Vidyadhara, S., et al. 2015. Int J Pharm Investig. 5: 101-6. PMID: 25838995
- Bioavailability Enhancement of Rizatriptan Benzoate by Oral Disintegrating Strip: In vitro and In vivo Evaluation. | Bhagawati, ST., et al. 2016. Curr Drug Deliv. 13: 462-70. PMID: 26310617
- An electrochemical sensor for rizatriptan benzoate determination using Fe3O4 nanoparticle/multiwall carbon nanotube-modified glassy carbon electrode in real samples. | Madrakian, T., et al. 2016. Mater Sci Eng C Mater Biol Appl. 63: 637-43. PMID: 27040259
- New formulation and approach for mucoadhesive buccal film of rizatriptan benzoate. | Salehi, S. and Boddohi, S. 2017. Prog Biomater. 6: 175-187. PMID: 29110144
- Design and optimization of kollicoat ® IR based mucoadhesive buccal film for co-delivery of rizatriptan benzoate and propranolol hydrochloride. | Salehi, S. and Boddohi, S. 2019. Mater Sci Eng C Mater Biol Appl. 97: 230-244. PMID: 30678908
- Comparative assessment of in vitro/in vivo performances of orodispersible electrospun and casting films containing rizatriptan benzoate. | Guo, X., et al. 2020. Eur J Pharm Biopharm. 154: 283-289. PMID: 32634573
- A novel rizatriptan oral gel formulation: Bioavailability and bioequivalence. | Tellone, V., et al. 2020. Int J Clin Pharmacol Ther. 58: 583-594. PMID: 32716291
- Formulation and Characterization of Nanostructured Lipid Carriers of Rizatriptan Benzoate-Loaded In Situ Nasal Gel for Brain Targeting. | Mathure, D., et al. 2022. Assay Drug Dev Technol. 20: 211-224. PMID: 35771865
- Assessment of nano lipid carrier loaded transdermal patch of rizatriptan benzoate. | Bhattacharyya, S. and Nanjareddy, L. 2022. Drug Metab Bioanal Lett.. PMID: 35794742
Activator of:
SR-1B, and SR-1D.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rizatriptan Benzoate, 10 mg | sc-219983 | 10 mg | $228.00 |