Ricinine (CAS 524-40-3)
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Ricinine is a natural alkaloid isolated from the seeds of the Ricinus communis plant, known widely for its role in the biosynthesis of ricin, a potent protein toxin. As a subject of interest in research, ricinine serves primarily as a marker to study the metabolic pathways and distribution of ricin in plant tissues. Its presence is pivotal for understanding the enzymatic processes involved in the synthesis of complex plant toxins, which can offer insights into plant defense mechanisms against pests and diseases. Ricinine′s distinctive chemical behavior also makes it useful in forensic science, especially for tracing the exposure to or the origin of ricin in environmental and forensic investigations. Researchers value ricinine for its utility in tracing biochemical and ecological interactions within Ricinus communis, providing a clearer view of the ecological roles and evolutionary strategies of this plant species.
Ricinine (CAS 524-40-3) References
- Ricinine and other constituents of Aparisthmium cordatum (Euphorbiaceae). | Souza, KM., et al. 2013. Nat Prod Res. 27: 364-70. PMID: 22708684
- Evaluation of ricinine, a ricin biomarker, from a non-lethal castor bean ingestion. | Hamelin, EI., et al. 2012. J Anal Toxicol. 36: 660-2. PMID: 23014889
- A metabonomic analysis of serum from rats treated with ricinine using ultra performance liquid chromatography coupled with mass spectrometry. | Peng, J., et al. 2014. PLoS One. 9: e90416. PMID: 24618672
- Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α. | Ohishi, K., et al. 2014. Bioorg Med Chem. 22: 4597-601. PMID: 25124862
- Optimization of Ultrasonic-Microwave Synergistic Extraction of Ricinine from Castor Cake by Response Surface Methodology. | Xu, W., et al. 2016. Curr Pharm Biotechnol. 17: 1126-1133. PMID: 27655362
- Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives. | El-Naggar, MH., et al. 2019. Nat Prod Res. 33: 1556-1562. PMID: 29334239
- Quantification of Ricinine and Abrine in Human Plasma by HPLC-MS-MS: Biomarkers of Exposure to Ricin and Abrin. | Isenberg, SL., et al. 2018. J Anal Toxicol. 42: 630-636. PMID: 29931062
- Lethal Injection of a Castor Bean Extract: Ricinine Quantification as a Marker for Ricin Exposure Using a Validated LC-MS/MS Method. | Verougstraete, N., et al. 2019. J Anal Toxicol. 43: e1-e5. PMID: 30590581
- Synthesis of new selective cytotoxic ricinine analogues against oral squamous cell carcinoma. | El-Naggar, MH., et al. 2021. Nat Prod Res. 35: 2145-2156. PMID: 31526148
- Isolation, characterization, and hepatoprotective properties of betulinic acid and ricinine from Tetracarpidium conophorum seeds (Euphorbiaceae). | Oriakhi, K., et al. 2021. J Food Biochem. 45: e13288. PMID: 32529649
- Fatal intoxication by intravenous injection of castor bean (Ricinus communis L.) extract-a case study. | Staňková, M., et al. 2020. Int J Legal Med. 134: 2133-2141. PMID: 32548760
- Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum. | Hien, DFDS., et al. 2021. Parasit Vectors. 14: 479. PMID: 34526119
- Effect of Salicylic Acid in the Yield of Ricinine in Ricinus communis under Greenhouse Condition. | Zavala-Gómez, CE., et al. 2021. Plants (Basel). 10: PMID: 34579435
- Evaluating the release and metabolism of ricinine from castor cake fertilizer in soils using a LC-QTOF/MS coupled with SIRIUS workflow. | Zheng, KX., et al. 2023. Chemosphere. 310: 136865. PMID: 36244422
- A novel quality-by-design optimized spectrofluorimetric method for the sensitive determination of ricinine alkaloid in edible oils. | Magdy, G., et al. 2023. Food Chem. 404: 134588. PMID: 36272302
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricinine, 100 mg | sc-477392 | 100 mg | $394.00 |