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Ricin B Antibody (RB363) is a mouse monoclonal IgG2b antibody that detects Ricin B from Ricinus communis by western blotting (WB). Ricin B, also known as Ricin B chain (RTB), plays a crucial role in ricin toxicity by facilitating A chain entry into target cells. RTB binds specifically to beta-D-galactopyranoside moieties present on glycoprotein surfaces, which enables A chain internalization and subsequent toxic effects. RTB′s interaction with cell surface carbohydrates highlights RTB′s importance in ricin toxicity mechanisms and potential as a therapeutic target for mitigating ricin exposure effects. Structural analysis of ricin has revealed distinct A and B chain domains, emphasizing RTB′s significance in ricin′s function. Anti-Ricin B antibody (RB363) serves as a valuable research tool for studying ricin toxicity mechanisms and related cellular pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricin B Antibody (RB363) | sc-52193 | 100 µg/ml | $322.00 |