Ricin B Antibody (RB257): sc-52192
- Ricin B Antibody (RB257) is a mouse monoclonal IgG2a Ricin B antibody, cited in 1 publications, provided at 100 µg/ml
- raised against Ricinus communis agglutinin
- recommended for detection of RAC120 and the B-chain of RCA60 of Ricinus communis origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ricin B Antibody (RB257). This work is in progress.
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Ricin B Antibody (RB257) is a mouse monoclonal IgG2a antibody that detects Ricin B protein of Ricinus communis origin by western blotting (WB). Anti-Ricin B antibody (RB257) is available as a non-conjugated format, providing a reliable tool for researchers studying this potent toxin. Ricin, a type II ribosomal inactivating protein, plays a critical role in inhibiting protein biosynthesis through RNA N-glycosidase activity, which is essential for understanding toxic mechanisms. Ricin B chain (RTB) functions as a lectin, facilitating toxin binding to target cells by recognizing and attaching to beta-D-galactopyranoside moieties present on glycoprotein surfaces. This binding allows A chain (RTA) to enter cells, where RTA exerts toxic effects by depurinating adenine 4324 in 28S rRNA of 60S ribosomal subunit, effectively halting protein synthesis. Crystal structure analysis of ricin has revealed important insights into functional domains and interactions, which can aid in developing therapeutic strategies against ricin poisoning.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ricin B Antibody (RB257) | sc-52192 | 100 µg/ml | $316.00 |