Ribosomal Protein S9 Antibody (E-3): sc-390614

Ribosomal Protein S9 Antibody (E-3) is a mouse monoclonal IgM kappa antibody that detects Ribosomal Protein S9 (RPS9) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RPS9 antibody (E-3) is available as the non-conjugated form. RPS9, also known as 40S ribosomal protein S9, plays a crucial role in the assembly and function of the ribosome, which is essential for protein synthesis in all living cells. This 194 amino acid protein contains one S4 RNA-binding domain and is a member of the ribosomal protein S4P family. RPS9 is primarily located in the cytoplasm, where RPS9 is part of the small ribosomal subunit (40S) and has been identified as a component of an mRNP granule complex, which is vital for the regulation of mRNA translation and stability. The gene encoding RPS9 is mapped to human chromosome 19q13.42 and exists as multiple processed pseudogenes scattered throughout the genome, reflecting the complexity of ribosomal protein gene families. RPS9′s ability to interact with various RNA molecules and other ribosomal proteins underscores RPS9′s importance in the intricate process of ribosome biogenesis and function, making RPS9 a significant target for research in cellular biology and disease mechanisms.

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Ribosomal Protein S9 Antibody (E-3) References:

1. Identification of genes responsive to BPDE treatment in HeLa cells using cDNA expression assays.  |  Yu, Z., et al. 2000. Environ Mol Mutagen. 36: 201-5. PMID: 11044901
2. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.  |  Yoshihama, M., et al. 2002. Genome Res. 12: 379-90. PMID: 11875025
3. Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes.  |  Yu, Y., et al. 2005. Protein Sci. 14: 1438-46. PMID: 15883184
4. Ribosomal protein S9 is a novel B23/NPM-binding protein required for normal cell proliferation.  |  Lindström, MS. and Zhang, Y. 2008. J Biol Chem. 283: 15568-76. PMID: 18420587
5. Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation.  |  Lindström, MS. and Nistér, M. 2010. PLoS One. 5: e9578. PMID: 20221446
6. Elucidation of motifs in ribosomal protein S9 that mediate its nucleolar localization and binding to NPM1/nucleophosmin.  |  Lindström, MS. 2012. PLoS One. 7: e52476. PMID: 23285058
7. [Ribosomal Protein S9 Expression in Multiple Myeloma and Its Effect on Cell Biological Function].  |  Song, KP., et al. 2019. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 41: 175-182. PMID: 31060671
8. Identification of ribosomal protein family in triple-negative breast cancer by bioinformatics analysis.  |  Lin, Z., et al. 2021. Biosci Rep. 41: PMID: 33305312
9. Analysis of 2166 clones from a human colorectal cancer cDNA library by partial sequencing.  |  Frigerio, JM., et al. 1995. Hum Mol Genet. 4: 37-43. PMID: 7711732
10. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.  |  Frigerio, JM., et al. 1995. Biochim Biophys Acta. 1262: 64-8. PMID: 7772601
11. The primary structure of rat ribosomal protein S9.  |  Chan, YL., et al. 1993. Biochem Biophys Res Commun. 193: 106-12. PMID: 8503895
12. A map of 75 human ribosomal protein genes.  |  Kenmochi, N., et al. 1998. Genome Res. 8: 509-23. PMID: 9582194

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ribosomal Protein S9 Antibody (E-3) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Ribosomal Protein S9 Antibody (E-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ribosomal Protein S9 Antibody (E-3) Specifications

Alternate Product Name: Ribosomal Protein S9

Product Clone Name: E-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 8-32

Epitope Target: Ribosomal Protein S9

Epitope Species: human

Product Reactivity/Detection: Ribosomal Protein S9

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Ribosomal Protein S9 Antibody (E-3): P: Blocking Peptide