Ribosomal Protein S17 Antibody (40-K): sc-100835

Ribosomal Protein S17 Antibody (40-K) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ribosomal Protein S17 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-Ribosomal Protein S17 antibody (40-K) is available as the non-conjugated format. Ribosomal Protein S17, also known as RPS17, RPS17L1, or RPS17L2, is a crucial component of the 40S ribosomal subunit, which plays a vital role in protein synthesis within the cytoplasm. This 135 amino acid protein is part of the S17e family of ribosomal proteins and is expressed ubiquitously, highlighting an essential function in cellular metabolism. Proper functioning of Ribosomal Protein S17 is particularly important as mutations in the gene encoding RPS17 have been linked to Diamond-Blackfan anemia (DBA), a rare congenital disorder that impairs pro-erythroblast differentiation, leading to anemia. Additionally, the gene for Ribosomal Protein S17 is characterized by multiple processed pseudogenes scattered throughout the genome, reflecting the complexity and evolutionary significance of ribosomal proteins in mammalian biology.

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Ribosomal Protein S17 Antibody (40-K) References:

1. Maize high chlorophyll fluorescent 60 mutation is caused by an Ac disruption of the gene encoding the chloroplast ribosomal small subunit protein 17.  |  Schultes, NP., et al. 2000. Plant J. 21: 317-27. PMID: 10758483
2. Characterization of rps17, rp19 and rpl15: three nucleus-encoded plastid ribosomal protein genes.  |  Thompson, MD., et al. 1992. Plant Mol Biol. 18: 931-44. PMID: 1581570
3. Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia.  |  Cmejla, R., et al. 2007. Hum Mutat. 28: 1178-82. PMID: 17647292
4. Molecular basis of Diamond-Blackfan anemia: structure and function analysis of RPS19.  |  Gregory, LA., et al. 2007. Nucleic Acids Res. 35: 5913-21. PMID: 17726054
5. Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray.  |  Liu, Y., et al. 2007. Oncol Rep. 18: 943-51. PMID: 17786358
6. RPS19 mutations in patients with Diamond-Blackfan anemia.  |  Campagnoli, MF., et al. 2008. Hum Mutat. 29: 911-20. PMID: 18412286
7. The Drosophila melanogaster RPS17 gene encoding ribosomal protein S17.  |  Maki, C., et al. 1989. Gene. 79: 289-98. PMID: 2507396
8. The transcriptionally active human ribosomal protein S17 gene.  |  Chen, IT. and Roufa, DJ. 1988. Gene. 70: 107-16. PMID: 3240863

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ribosomal Protein S17 Antibody (40-K) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-Ribosomal Protein S17 Antibody (40-K) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ribosomal Protein S17 Antibody (40-K) Specifications

Alternate Product Name: Ribosomal Protein S17

Product Clone Name: 40-K

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 36-136

Epitope Target: Ribosomal Protein S17

Epitope Species: human

Product Reactivity/Detection: Ribosomal Protein S17

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 50 µg IgG₁ kappa light chain in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for Ribosomal Protein S17 Antibody (40-K): N/A