Ribosomal Protein S10 Antibody (A-10): sc-515655
- Ribosomal Protein S10 Antibody (A-10) is a mouse monoclonal IgG1 κ Ribosomal Protein S10 antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 105-124 within an internal region of Ribosomal Protein S10 of human origin
- Ribosomal Protein S10 Antibody (A-10) is recommended for detection of Ribosomal Protein S10 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Ribosomal Protein S10 Antibody (A-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for Ribosomal Protein S10 Antibody (A-10) for WB applications. This reagent is now offered in a bundle with Ribosomal Protein S10 Antibody (A-10) (see ordering information below).
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Ribosomal Protein S10 Antibody (A-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ribosomal Protein S10 (RPS10) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RPS10 antibody (A-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RPS10 is a crucial 165 amino acid component of the small ribosomal 40S subunit, playing a vital role in the assembly and function of ribosomes, which are essential for protein synthesis in all living cells. RPS10 is primarily located in the cytoplasm but can also localize to the granular component of the nucleolus, a process that requires methylation by protein arginine methyltransferase 5 (PRMT5) and interaction with nucleolar protein 1 (NPS1). This localization is significant as it suggests a regulatory role for RPS10 in ribosome biogenesis and cellular stress responses. Defects in RPS10 are associated with Diamond-Blackfan anemia type 9 (DBA9), a serious congenital condition characterized by non-regenerative hypoplastic anemia, which typically manifests in infancy and is marked by macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. RPS10 monoclonal antibody (A-10) is an invaluable tool for researchers studying ribosome function, protein synthesis, and related hematological disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ribosomal Protein S10 Antibody (A-10) References:
- A quantitative atlas of mitotic phosphorylation. | Dephoure, N., et al. 2008. Proc Natl Acad Sci U S A. 105: 10762-7. PMID: 18669648
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. | Daub, H., et al. 2008. Mol Cell. 31: 438-48. PMID: 18691976
- Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. | Wang, B., et al. 2008. Anal Chem. 80: 9526-33. PMID: 19007248
- An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells. | Heibeck, TH., et al. 2009. J Proteome Res. 8: 3852-61. PMID: 19534553
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. | Mayya, V., et al. 2009. Sci Signal. 2: ra46. PMID: 19690332
- Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. | Doherty, L., et al. 2010. Am J Hum Genet. 86: 222-8. PMID: 20116044
- Methylation of ribosomal protein S10 by protein-arginine methyltransferase 5 regulates ribosome biogenesis. | Ren, J., et al. 2010. J Biol Chem. 285: 12695-705. PMID: 20159986
- Initial characterization of the human central proteome. | Burkard, TR., et al. 2011. BMC Syst Biol. 5: 17. PMID: 21269460
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ribosomal Protein S10 Antibody (A-10) | sc-515655 | 200 µg/ml | $316.00 | |||
Ribosomal Protein S10 Antibody (A-10): m-IgG1 BP-HRP Bundle | sc-531809 | 200 µg Ab; 20 µg BP | $354.00 | |||
Ribosomal Protein S10 Antibody (A-10) AC | sc-515655 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Ribosomal Protein S10 Antibody (A-10) HRP | sc-515655 HRP | 200 µg/ml | $316.00 | |||
Ribosomal Protein S10 Antibody (A-10) FITC | sc-515655 FITC | 200 µg/ml | $330.00 | |||
Ribosomal Protein S10 Antibody (A-10) PE | sc-515655 PE | 200 µg/ml | $343.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 488 | sc-515655 AF488 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 546 | sc-515655 AF546 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 594 | sc-515655 AF594 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 647 | sc-515655 AF647 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 680 | sc-515655 AF680 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 Antibody (A-10) Alexa Fluor® 790 | sc-515655 AF790 | 200 µg/ml | $357.00 | |||
Ribosomal Protein S10 (A-10) Neutralizing Peptide | sc-515655 P | 100 µg/0.5 ml | $68.00 |