Date published: 2026-5-11

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Ribavirin 5′-Triphosphate sodium salt (CAS 63142-71-2 (non-salt))

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Alternate Names:
1--D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5′-triphosphate, Sodium salt
Application:
Ribavirin 5′-Triphosphate sodium salt is a metabolite of Ribavirin
CAS Number:
63142-71-2 (non-salt)
Purity:
>95%
Molecular Weight:
484.14 (free acid)
Molecular Formula:
C8H15N4O14P3 (free acid)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ribavirin 5′-Triphosphate sodium salt is a metabolite of Ribavirin. Ribavirin 5′-triphosphate (RTP), a nucleoside analog, has garnered attention for its potential antiviral properties. Research suggests that RTP can impede viral replication by disrupting the replication machinery of viruses. It is postulated that RTP binds to the viral RNA polymerase, hindering its function and ultimately preventing viral replication, resulting in the demise of the virus. This mechanism underscores the potential of Ribavirin 5′-triphosphate as an antiviral agent with promising applications in combating viral infections.


Ribavirin 5′-Triphosphate sodium salt (CAS 63142-71-2 (non-salt)) References

  1. Pharmacokinetics and metabolism of [(14)C]ribavirin in rats and cynomolgus monkeys.  |  Lin, CC., et al. 2003. Antimicrob Agents Chemother. 47: 1395-8. PMID: 12654676
  2. Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5'-triphosphates in human blood and L5178Y cells.  |  Zimmerman, TP. and Deeprose, RD. 1978. Biochem Pharmacol. 27: 709-16. PMID: 207278
  3. Synthesis and antiviral acticity of some phosphates of the broad-spectrum antiviral nucleoside, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin).  |  Allen, LB., et al. 1978. J Med Chem. 21: 742-6. PMID: 211234
  4. The metabolism of ribavirin in erythrocytes and nucleated cells.  |  Page, T. and Connor, JD. 1990. Int J Biochem. 22: 379-83. PMID: 2159925

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ribavirin 5′-Triphosphate sodium salt, 20 units

sc-358826
20 units
$332.00