Rhodamine 123 CAS: 62669-70-9
MF: C21H17N2O3•Cl
MW: 380.82
A cationic dye that emits a green fluorescence.

Rhodamine 123 (CAS 62669-70-9)

Rhodamine 123 | CAS 62669-70-9 is rated 5.0 out of 5 by 1.
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Alternate Names: Rhodamin 123 Chloride; 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester
Application: Rhodamine 123 is a cationic dye that emits a green fluorescence
CAS Number: 62669-70-9
Molecular Weight: 380.82
Molecular Formula: C21H17N2O3•Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Rhodamine 123 is a cationic dye that emits a green fluorescence. Research observations indicate that Rhodamine 123 can be used to probe the electrochemical gradient in mitochondria, in flow cytometry to detect the activity of P-glycoprotein efflux, and as a compound for P-GP mediating transport. Studies report that Rhodamine 123 can decrease the clonal growth of carcinoma cells in vitro, and that it can associate with placental P-gp. Rhodamine 123 is a substrate of Mdr (P-glycoprotein). Rhodamine 123 is a substrate of MRP1.


References

1. Bernal, S.D., et al. 1982. Science. 218: 1117-1119. PMID: 7146897
2. Ferlini, C., et al. 2007. Nat Protoc. 2: 3111-3114. PMID: 18079710
3. Kahlert, S., et al. 2008. J. Neurosci. Methods. 171: 87-92. PMID: 18400303
4. Cygalova, L.H., et al. 2009. J. Pharmacol. Exp. Ther. 331: 1118-1125. PMID: 19779128
5. Munić, V., et al. 2010. Eur J Pharm Sci. 41: 86-95. PMID: 20621639

Physical State :
Solid
Solubility :
Soluble in ethanol (20 mg/ml), DMSO, methanol, and water (partly miscible).
Storage :
Store at -20° C
Melting Point :
235° C
Fluoresence :
λex 507 nm, λem 529 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
ZE0883000
PubChem CID :
65217
Merck Index :
14: 10356
MDL Number :
MFCD00012664
EC Number :
263-687-8
Beilstein Registry :
6030951
SMILES :
COC(=O)C1=CC=CC=C1C2=C3C=CC(=[NH2+])C=C3OC4=C2C=CC(=C4)N.[Cl-]

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Rhodamine 123 (CAS 62669-70-9) Product Citations

See how others have used Rhodamine 123 (CAS 62669-70-9). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 11 total

PMID: # 26893616  Huang, FC. et al. 2016. Gut pathogens. 8: 5.

PMID: # 26134503  Choi, AR. et al. 2015. Eur. J. Pharmacol. 764: 63-9.

PMID: # 25778901  Seo, K. et al. 2015. Cellular signalling. 27: 1533-43.

PMID: # 24681519  Ramos-Mandujano, G. et al. 2014. Stem cell research. 12: 690-702.

PMID: # 25151220  Seo, K. et al. 2014. Toxicol. Appl. Pharmacol. 280: 314-22.

PMID: # 21573958  Kim, WK. et al. 2012. Invest New Drugs. 30: 1311-8.

PMID: # 23202945  Kim, JH. et al. 2012. Int J Mol Sci. 13: 13169-82.

PMID: # 22168362  Zherebitskaya, E. et al. 2012. ASN Neuro. 4: -.

PMID: # 21856397  Wu, Q. et al. 2011. Journal of ethnopharmacology. 138: 34-9.

PMID: # 27235784  Ugwu, MC. et al. J Pharmacol Toxicol Methods. 82: 9-19.

Citations 1 to 10 of 11 total

Good morning! What’s  purity rodamine 123 number sc-208306?

Asked by: Letta123
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Answered by: Technical Support
Date published: 2018-12-06

hi team, if I dissolve rhodamine 123 1mg/ml with methanol, for how long the sample will be stable in 4C?

Asked by: TETA
Thank you for your question! Rhodamine 123 is soluble in methanol. As a solution at 4˚C it should be stable for weeks if protected from light. As a solid it is very stable. If you have any further questions, please contact our European Technical Service team. You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: [email protected] or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-03-09
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Rated 5 out of 5 by from Various publications cite the use of Rhodamine Various publications cite the use of Rhodamine 123 to probe the electrochemical gradient in mitochondria, in flow cytometry to detect the activity of P-glycoprotein efflux, and as a compound for P-GP mediating transport. -SCBT Publication Review
Date published: 2015-06-14
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