Date published: 2026-4-24

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Rhodamine 101 Inner Salt (CAS 116450-56-7)

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Application:
Rhodamine 101 Inner Salt is one of the brightest fluorescent dyes used in various biological applications
CAS Number:
116450-56-7
Molecular Weight:
490.59
Molecular Formula:
C32H30N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Rhodamine 101 Inner Salt (CAS: 116450-56-7) is a derivative of the rhodamine family, a group of compounds well-known for their intense fluorescence properties. This particular chemical is characterized by its inner salt structure, also known as a zwitterion, where the molecule contains both positively and negatively charged groups but is overall electrically neutral. This structural feature enhances its solubility in polar solvents while maintaining strong luminescent properties. Rhodamine 101 Inner Salt exhibits a bright red fluorescence when excited by light, typically in the green to yellow range of the spectrum, making it an excellent dye for various applications in scientific research that require high levels of fluorescence stability and intensity. In research settings, Rhodamine 101 Inner Salt is utilized primarily as a fluorescent probe in the study of dynamic processes within cells and tissues, as well as in environmental tracing and analysis. The mechanism of action relies on its ability to absorb light at specific wavelengths and subsequently emit light at a longer wavelength, a property that can be exploited to track and measure biological and chemical processes with high precision. Moreover, due to its strong photostability and the bright nature of its fluorescence, it is frequently used in fluorescence microscopy and spectroscopy techniques. This includes applications such as tracing the distribution of pollutants in water systems or studying the movement and interactions of molecules within live cells, where its distinct fluorescence allows for clear visualization and analysis of complex biological structures and reactions.


Rhodamine 101 Inner Salt (CAS 116450-56-7) References

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  2. A nanoparticle-based ratiometric and self-calibrated fluorescent thermometer for single living cells.  |  Takei, Y., et al. 2014. ACS Nano. 8: 198-206. PMID: 24354266
  3. Loading and Release of Charged and Neutral Fluorescent Dyes into and from Mesoporous Materials: A Key Role for Sensing Applications.  |  Climent, E., et al. 2021. Micromachines (Basel). 12: PMID: 33671037
  4. Full theoretical protocol for the design of metal-free organic electron donor-spacer-acceptor systems.  |  Duque-Prata, A., et al. 2023. Phys Chem Chem Phys. 25: 27854-27865. PMID: 37814945
  5. Dopamine-loaded chitosan-coated solid lipid nanoparticles as a promise nanocarriers to the CNS.  |  Ortega Martínez, E., et al. 2024. Neuropharmacology. 249: 109871. PMID: 38412889
  6. Shedding light on imaging safety: Decoding the origin of photocytotoxicity in RhB-assisted fluorescence imaging.  |  Luo, C., et al. 2024. J Biophotonics. 17: e202400049. PMID: 38634340
  7. Adsorption and photocatalytic degradation behaviors of rhodamine dyes on surface-fluorinated TiO 2 under visible irradiation[J].  |  Guo J, Yuan S, Jiang W. 2016. RSC advances. 6(5): 4090-4100.
  8. Compatibility of organic solvents for electrochemical measurements in PDMS-based microfluidic devices[J].  |  Adamiak W, Kałuża D, Jönsson-Niedziolka M. 2016. Microfluidics and Nanofluidics,. 20: 1-7.
  9. Performance Evaluation of Solid State Luminescent Solar Concentrators Based on InP/ZnS-Rhodamine 101 Hybrid Inorganic–Organic Luminophores[J].  |  Gordon C K, Hogg R F, Brett M W. 2022. The Journal of Physical Chemistry C. 126(46): 19803-19815.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rhodamine 101 Inner Salt, 500 mg

sc-212775
500 mg
$165.00