Molecular structure of RHOD 2/AM, CAS Number: 129787-64-0
RHOD 2/AM (CAS 129787-64-0)
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Application:
RHOD 2/AM is a membrane permeable fluoregenic probe for intracellular Ca2+
CAS Number:
129787-64-0
Purity:
>90%
Molecular Weight:
1123.96
Molecular Formula:
C52H59N4O19•Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
RHOD 2/AM is a membrane permeable form of RHOD 2 which operates in the visible spectrum. Used as a fluorescent probe for intracellular Ca2+. RHOD 2/AM binds to Ca2+ once it is hydrolyzed to RHOD 2 by endogenous esterases inside cells. RHOD-2/AM has applications in electrophysiology where it serves as useful for measuring the electrical activity of neurons and investigating the impact of drugs on neuronal function. Moreover, it has proven useful in drug discovery processes, enabling the detection of drug-protein interactions and facilitating the study of drug mechanisms of action.
RHOD 2/AM (CAS 129787-64-0) References
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- Shengmai injection alleviates H2O2‑induced oxidative stress through activation of AKT and inhibition of ERK pathways in neonatal rat cardiomyocytes. | Zhu, J., et al. 2019. J Ethnopharmacol. 239: 111677. PMID: 30615921
- Pre-treatment with a combination of Shenmai and Danshen injection protects cardiomyocytes against hypoxia/reoxygenation- and H2O2-induced injury by inhibiting mitochondrial permeability transition pore opening. | Li, L., et al. 2019. Exp Ther Med. 17: 4643-4652. PMID: 31086595
- Simultaneous Ca2+ Imaging and Optogenetic Stimulation of Cortical Astrocytes in Adult Murine Brain Slices. | Balachandar, L., et al. 2020. Curr Protoc Neurosci. 94: e110. PMID: 33285041
- Confocal microscopy to analyze cytosolic and nuclear calcium in cultured vascular cells. | Burnier, M., et al. 1994. Am J Physiol. 266: C1118-27. PMID: 8178959
- Confocal microscopy reveals coordinated calcium fluctuations and oscillations in synaptic boutons. | Melamed, N., et al. 1993. J Neurosci. 13: 632-49. PMID: 8426230
- Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes. | Trollinger, DR., et al. 1997. Biochem Biophys Res Commun. 236: 738-42. PMID: 9245725
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RHOD 2/AM, 1 mg | sc-202790 | 1 mg | $282.00 |