Molecular structure of Rho Kinase Inhibitor III, Rockout, CAS Number: 7272-84-6
Rho Kinase Inhibitor III, Rockout (CAS 7272-84-6)
See product citations (1)
Alternate Names:
3-(4-Pyridyl)-1H-indole
Application:
Rho Kinase Inhibitor III, Rockout is a selective, ATP-competitive Rho kinase activity inhibitor
CAS Number:
7272-84-6
Purity:
≥98%
Molecular Weight:
194.23
Molecular Formula:
C13H10N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Rho Kinase Inhibitor III, Rockout is a cell permeable ATP-competitive Rock (Rho Kinase) inhibitor discovered by an image based, high throughput screen of a wound healing cell monolayer. When discovered Rock (Rho Kinase) Inhibitor III, Rockout was observed to not be toxic while inhibiting blebbing and promoting cell spreading. The compound was observed to inhibit the blebbing of recently trypsinized Swiss3T3 cells and M2 cells. The Inhibitor was documented to have an IC50 =12 mu
Rho Kinase Inhibitor III, Rockout (CAS 7272-84-6) References
- Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor. | Yarrow, JC., et al. 2005. Chem Biol. 12: 385-95. PMID: 15797222
Inhibitor of:
ARHGAP23, Enzyme, and Rock.Activator of:
Caldesmon, and Rpp38.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rho Kinase Inhibitor III, Rockout, 5 mg | sc-203237 | 5 mg | $74.00 |