Retinal Cell Marker Antibody (3BA8): sc-80976

Retinal Cell Marker Antibody (3BA8) is a mouse monoclonal IgM antibody that detects the Retinal Cell Marker protein of avian origin by immunofluorescence (IF). Anti-Retinal Cell Marker antibody (3BA8) is available as the non-conjugated format. Retinal Cell Marker (3BA8) antibody enables identification and characterization of retinal cells, essential for understanding various retinal disorders and developing targeted therapies. Located primarily in the outer layers of the retina, Retinal Cell Marker plays a crucial role in the differentiation and maintenance of photoreceptor cells, including rods and cones, vital for vision. Rods are responsible for low-light vision, while cones enable color perception and high-resolution sight. Proper functioning of these cells is critical, as any disruption can lead to severe visual impairments or diseases such as retinitis pigmentosa and macular degeneration. Anti-Retinal Cell Marker antibody (3BA8) helps researchers gain valuable insights into cellular mechanisms of the retina and pathophysiology of retinal diseases, ultimately contributing to advancements in ocular health and treatment strategies.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

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Retinal Cell Marker Antibody (3BA8) References:

1. Transduction in retinal photoreceptor cells.  |  Baylor, D. 1992. Soc Gen Physiol Ser. 47: 151-74. PMID: 1369760
2. Phototransduction motifs and variations.  |  Yau, KW. and Hardie, RC. 2009. Cell. 139: 246-64. PMID: 19837030
3. Why do cone photoreceptors die in rod-specific forms of retinal degenerations?  |  Koenekoop, RK. 2009. Ophthalmic Genet. 30: 152-4. PMID: 19941421
4. Retinal light damage: mechanisms and protection.  |  Organisciak, DT. and Vaughan, DK. 2010. Prog Retin Eye Res. 29: 113-34. PMID: 19951742
5. Functional architecture of the mammalian retina.  |  Wässle, H. and Boycott, BB. 1991. Physiol Rev. 71: 447-80. PMID: 2006220
6. [Macular dystrophies--hereditary macular degenerations].  |  Walter, P. and Mazinani, B. 2010. Klin Monbl Augenheilkd. 227: R1-R14. PMID: 20091442
7. Light response of vertebrate photoreceptors.  |  McNaughton, PA. 1990. Physiol Rev. 70: 847-83. PMID: 2194224
8. The photophysiology of vertebrate color vision.  |  Ripps, H. and Weale, RA. 1970. Photophysiology. 5: 127-68. PMID: 4950131

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Retinal Cell Marker Antibody (3BA8) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Retinal Cell Marker Antibody (3BA8) Specifications

Alternate Product Name: Retinal Cell Marker

Product Clone Name: 3BA8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: Retinal Cell Marker

Epitope Species: chicken

Product Reactivity/Detection: an antigen expressed by peripapillary glial cells, some amacrine cells and some cells in the ganglion cell layer

Species Reactivity/Detection: avian

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Retinal Cell Marker Antibody (3BA8): N/A