Date published: 2025-12-24

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Reticulum Cell Antibody (X-12): sc-59350

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Datasheets
  • Reticulum Cell Antibody (X-12) is a mouse monoclonal IgG1 Reticulum Cell antibody provided at 100 µg/ml
  • raised against mononuclear peripheral blood cells of human origin
  • recommended for detection of reticulum cells of human origin by IF, IHC(P) and FCM
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Reticulum Cell Antibody (X-12). This work is in progress.

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    Reticulum Cell Antibody (X-12) is a mouse monoclonal IgG1 antibody that detects the Reticulum Cell protein of human origin by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-Reticulum Cell antibody (X-12) is available as a non-conjugated format, providing researchers with a versatile tool for studying these important cells. Reticulum cells, which are integral components of the reticuloendothelial system, play a crucial role in the immune response, particularly within the T cell areas of lymph nodes and the spleen. These cells are essential for the maintenance of immune homeostasis and the regulation of lymphocyte activation and differentiation. Additionally, reticulum cells are involved in various pathological conditions, including tumors, where they can influence tumor microenvironments and immune evasion mechanisms. Understanding the interactions between reticulum cells and specific proteins, such as cytokines and growth factors, is vital for elucidating their roles in both normal physiology and disease states. Reticulum Cell monoclonal antibody (X-12) enables researchers to gain insights into the dynamics of these cells and their contributions to immune responses and tumor biology.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Reticulum Cell Antibody (X-12) References:

    1. Cytokeratin-positive malignant tumors with reticulum cell morphology: a subtype of fibroblastic reticulum cell neoplasm?  |  Chan, AC., et al. 2000. Am J Surg Pathol. 24: 107-16. PMID: 10632494
    2. Classic follicular dendritic reticulum cell tumor of the lymph node developing in a patient with a previous inflammatory pseudotumor-like proliferation.  |  Cossu, A., et al. 2005. Hum Pathol. 36: 207-11. PMID: 15754299
    3. Interdigitating dendritic reticulum cell sarcoma: cytologic, histologic and immunocytochemical features.  |  Jayaram, G., et al. 2005. Diagn Cytopathol. 33: 43-8. PMID: 15945093
    4. Spindle cell neoplasms of lymph nodes of probable reticulum cell lineage. True reticulum cell sarcoma?  |  Weiss, LM., et al. 1990. Am J Surg Pathol. 14: 405-14. PMID: 2158241
    5. Reticulum cell neoplasms induced in C57BL/6 mice by cultured virus grown in stromal hematopoietic cell lines.  |  Haas, M. and Meshorer, A. 1979. J Natl Cancer Inst. 63: 427-39. PMID: 222931
    6. Inhibition of IA positive reticulum cell sarcoma tumor cell growth in syngeneic SJL/J mice by passive administration of monoclonal anti-IA antibody.  |  Sakano, T. and Bonavida, B. 1986. Cancer Res. 46: 3245-8. PMID: 3518916
    7. Reticulum cell neoplasms of lymph nodes: a clinicopathologic study of 11 cases with recognition of a new subtype derived from fibroblastic reticular cells.  |  Andriko, JW., et al. 1998. Am J Surg Pathol. 22: 1048-58. PMID: 9737236
    8. Interdigitating reticulum cell tumor of lymph node: a case report and literature review.  |  Liu, SM., et al. 1998. Pathol Int. 48: 974-80. PMID: 9952342
    9. Involvement of peritoneal macrophages and spleen stromal cells in X-irradiation-induced reticulum cell neoplasms in C57BL/6 mice.  |  Sher, T., et al. 1982. Leuk Res. 6: 519-29. PMID: 6755073

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Reticulum Cell Antibody (X-12)

    sc-59350
    100 µg/ml
    $316.00