Date published: 2025-12-24

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Respiratory Syncytial Virus Antibody (8C5): sc-52182

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Datasheets
  • Respiratory Syncytial Virus Antibody (8C5) is a mouse monoclonal IgG2b provided at 100 µg/ml
  • raised against purified respiratory syncytial virus, strain Long
  • recommended for detection of surface glycoprotein G of RSV of Respiratory Syncytial Virus origin by ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Respiratory Syncytial Virus Antibody (8C5). This work is in progress.

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    Respiratory Syncytial Virus Antibody (8C5) is a mouse monoclonal IgG2b antibody that specifically detects Respiratory Syncytial Virus (RSV) through enzyme-linked immunosorbent assay (ELISA). RSV monoclonal antibody (8C5) recognizes RSV, a significant pathogen causing severe respiratory illnesses, particularly in infants and young children. RSV′s fusion protein plays a crucial role in pathogenicity by facilitating viral and host cell membrane fusion, essential for viral entry into host cells. This fusion process enables virus penetration through host defenses and leads to syncytia formation, contributing to respiratory tract tissue damage and inflammation. Understanding fusion protein function remains vital for developing targeted therapies and vaccines, representing a key intervention point in viral life cycles. Anti-RSV antibody (8C5) serves as an invaluable research tool for studying RSV infection mechanisms and immune responses, providing insights toward improved treatment strategies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Respiratory Syncytial Virus Antibody (8C5) References:

    1. The relationship between respiratory syncytial virus and asthma.  |  Knudson, CJ. and Varga, SM. 2015. Vet Pathol. 52: 97-106. PMID: 24513802
    2. Mucosal vaccines against respiratory syncytial virus.  |  Yang, K. and Varga, SM. 2014. Curr Opin Virol. 6: 78-84. PMID: 24794644
    3. The significance of transplacental antibody against respiratory syncytial virus.  |  Piedra, PA. and Munoz, FM. 2014. J Infect Dis. 210: 1526-8. PMID: 24903668
    4. Respiratory Syncytial Virus During Pregnancy.  |  Polack, FP. 2018. Clin Infect Dis. 66: 1666-1667. PMID: 29253107
    5. Vaccination against Respiratory Syncytial Virus.  |  Green, CA., et al. 2020. Interdiscip Top Gerontol Geriatr. 43: 182-192. PMID: 32305982
    6. Mucosal Immune Responses to Respiratory Syncytial Virus.  |  Barnes, MVC., et al. 2022. Cells. 11: PMID: 35406717
    7. The road to approved vaccines for respiratory syncytial virus.  |  Ruckwardt, TJ. 2023. NPJ Vaccines. 8: 138. PMID: 37749081
    8. Defining the Assembleome of the Respiratory Syncytial Virus.  |  Sugrue, RJ. and Tan, BH. 2023. Subcell Biochem. 106: 227-249. PMID: 38159230
    9. Microbiological and epidemiological features of respiratory syncytial virus.  |  Sanz-Muñoz, I., et al. 2024. Rev Esp Quimioter. 37: 209-220. PMID: 38515332
    10. Respiratory syncytial virus vaccination in pregnancy.  |  Abu-Raya, B., et al. 2024. CMAJ. 196: E1118-E1119. PMID: 39353630

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Respiratory Syncytial Virus Antibody (8C5)

    sc-52182
    100 µg/ml
    $316.00