Molecular structure of Resorufin benzyl ether, CAS Number: 87687-02-3
Resorufin benzyl ether (CAS 87687-02-3)
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Alternate Names:
7-(benzyloxy)-3H-phenoxazin-3-one; Benzyloxyresorufin
Application:
Resorufin benzyl ether is a fluorogenic substrate for cytochrome P450-linked enzymes
CAS Number:
87687-02-3
Molecular Weight:
303.31
Molecular Formula:
C19H13NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Resorufin benzyl ether, a synthetic compound, has found extensive applications in diverse scientific research endeavors. It has been utilized to investigate enzyme activity, protein-protein interactions, and DNA-protein interactions. Furthermore, the compound Benzyloxyresorufin has been employed to examine the impact of drugs on cells and tissues. Resorufin benzyl ether is thought to function as an inhibitor of various enzymes, including monoamine oxidase, tyrosine hydroxylase, and choline acetyltransferase. Additionally, Resorufin benzyl ether believed to act as an agonist of adenosine receptors, potentially accounting for its effects on cells and tissues.
Resorufin benzyl ether (CAS 87687-02-3) References
- Inhibition of CYP3A4 in a rapid microtiter plate assay using recombinant enzyme and in human liver microsomes using conventional substrates. | Nomeir, AA., et al. 2001. Drug Metab Dispos. 29: 748-53. PMID: 11302943
- Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. | Zou, L., et al. 2002. Life Sci. 71: 1579-89. PMID: 12127912
- Design and application of fluorometric assays for human cytochrome P450 inhibition. | Crespi, CL., et al. 2002. Methods Enzymol. 357: 276-84. PMID: 12424917
- Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. | Yale, SH. and Glurich, I. 2005. J Altern Complement Med. 11: 433-9. PMID: 15992226
- Observational study of hepatic cytochrome P-450 protein expression and activity in summer flounder (Paralichtys dentatus) after combination ormetoprim-sulfadimethoxine treatment. | Topic Popovic, N., et al. 2007. Chemotherapy. 53: 313-5. PMID: 17728539
- Cross-sectional study of hepatic CYP1A and CYP3A enzymes in hybrid striped bass, channel catfish and Nile tilapia following oxytetracycline treatment. | Topic Popovic, N., et al. 2012. Res Vet Sci. 92: 283-91. PMID: 21458012
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- Induction of hepatic cytochrome P-450 mediated alkoxyresorufin O-dealkylase activities in different species by prototype P-450 inducers. | Lubet, RA., et al. 1990. Chem Biol Interact. 75: 325-39. PMID: 2379261
- Hediste diversicolor as bioindicator of pharmaceutical pollution: Results from single and combined exposure to carbamazepine and caffeine. | Pires, A., et al. 2016. Comp Biochem Physiol C Toxicol Pharmacol. 188: 30-8. PMID: 27327394
- Differential metabolism of imidacloprid and dinotefuran by Bemisia tabaci CYP6CM1 variants. | Hamada, A., et al. 2019. Pestic Biochem Physiol. 159: 27-33. PMID: 31400781
- Paper-based sol-gel thin films immobilized cytochrome P450 for enzyme activity measurement. | Nuchtavorn, N., et al. 2020. Anal Chim Acta. 1098: 86-93. PMID: 31948590
- Differential metabolism of neonicotinoids by brown planthopper, Nilaparvata lugens, CYP6ER1 variants. | Hamada, A., et al. 2020. Pestic Biochem Physiol. 165: 104538. PMID: 32359560
- 3D-Hepatocyte Culture Applied to Parasitology: Immune Activation of Canine Hepatic Spheroids Exposed to Leishmania infantum. | Rodrigues, AV., et al. 2020. Biomedicines. 8: PMID: 33352885
- Enzyme Mimic Facilitated Artificial Cell to Mammalian Cell Signal Transfer. | Qian, X., et al. 2021. Angew Chem Int Ed Engl. 60: 18704-18711. PMID: 34096152
Substrate of:
CYP, and Fluorogenic.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Resorufin benzyl ether, 5 mg | sc-208301 | 5 mg | $98.00 | |||
Resorufin benzyl ether, 10 mg | sc-208301A | 10 mg | $166.00 |