Date published: 2025-10-3

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Resibufogenin (CAS 465-39-4)

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Application:
Resibufogenin is a specific inhibitor of Na+/K+-ATPase
CAS Number:
465-39-4
Purity:
≥98%
Molecular Weight:
384.5
Molecular Formula:
C24H32O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Resibufogenin has a specific Na+/K+-ATPase inhibitor.


Resibufogenin (CAS 465-39-4) References

  1. Effects of resibufogenin from toad venom on isolated Purkinje fibers.  |  Xie, JT., et al. 2000. Am J Chin Med. 28: 187-96. PMID: 10999437
  2. Resibufogenin corrects hypertension in a rat model of human preeclampsia.  |  Vu, H., et al. 2006. Exp Biol Med (Maywood). 231: 215-20. PMID: 16446498
  3. Resibufogenin administration prevents oxidative stress in a rat model of human preeclampsia.  |  Uddin, MN., et al. 2012. Hypertens Pregnancy. 31: 70-8. PMID: 21174582
  4. Novel microbial transformation of resibufogenin by Fusarium solani.  |  Xin, XL., et al. 2011. J Asian Nat Prod Res. 13: 831-7. PMID: 21830888
  5. Separation and determination of resibufogenin and cinobufagin in Chansu using reversed-phase liquid chromatography with γ-cyclodextrin as mobile-phase modifier.  |  Xing, J., et al. 2012. J Sep Sci. 35: 1884-92. PMID: 22623502
  6. Isolation and identification of phase I metabolites of resibufogenin in rats.  |  Zhu, ZT., et al. 2013. Xenobiotica. 43: 479-85. PMID: 23153055
  7. Biotransformation of resibufogenin by Actinomucor elegans.  |  Mou, LY., et al. 2014. J Asian Nat Prod Res. 16: 623-8. PMID: 24911667
  8. Resibufogenin Induces G1-Phase Arrest through the Proteasomal Degradation of Cyclin D1 in Human Malignant Tumor Cells.  |  Ichikawa, M., et al. 2015. PLoS One. 10: e0129851. PMID: 26121043
  9. Resibufogenin Suppresses Triple-Negative Breast Cancer Angiogenesis by Blocking VEGFR2-Mediated Signaling Pathway.  |  Yang, T., et al. 2021. Front Pharmacol. 12: 682735. PMID: 33995111
  10. Resibufogenin, one of bufadienolides in toad venom, suppresses LPS-induced inflammation via inhibiting NF-κB and AP-1 pathways.  |  Gao, Y., et al. 2022. Int Immunopharmacol. 113: 109312. PMID: 36252491

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Resibufogenin, 10 mg

sc-202788
10 mg
$315.00
US: Only available in the US