Molecular structure of Reboxetine mesylate, CAS Number: 98769-84-7
Reboxetine mesylate (CAS 98769-84-7)
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Application:
Reboxetine mesylate is a potent selective inhibitor of noradrenalin uptake
CAS Number:
98769-84-7
Purity:
≥99%
Molecular Weight:
409.5
Molecular Formula:
C19H23NO3 CH3SO3H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Reboxetine mesylate is a potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors.
Reboxetine mesylate (CAS 98769-84-7) References
Sacchetti et al (1999) Studies on the acute and chronic effects of reboxetine on extracellular noradrenaline and other monoamines in the rat brain. Br.J.Pharmacol. 128 1332. Wong et al (2000) Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor. Biol.Psychiatry. 47 818. Millan et al (2001) S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J.Pharmacol.Exp.Ther. 298 565. Owen and Whitton (2003) Reboxetine modulates norepinephrine efflux in the frontal cortex of the freely moving rat: the involvement of a2 and 5-HT1A receptors. Neurosci.Lett. 348 171.Inhibitor of:
SLC6A2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Reboxetine mesylate, 10 mg | sc-204232 | 10 mg | $264.00 | |||
Reboxetine mesylate, 50 mg | sc-204232A | 50 mg | $1000.00 |