Molecular structure of Rebamipide, CAS Number: 90098-04-7
Rebamipide (CAS 90098-04-7)
See product citations (1)
Alternate Names:
2-(4-Chlorobenzamido)-3-[2(1H)-quinolinon-4-yl]propionic Acid
Application:
Rebamipide is an inducer of endogenous prostaglandin and a oxygen-derived free radical scavenger
CAS Number:
90098-04-7
Purity:
≥98%
Molecular Weight:
370.79
Molecular Formula:
C19H15ClN2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Rebamipide is a chemical that functions as a cytoprotective agent in experimental applications. It acts by increasing the production of mucin and bicarbonate in the gastric mucosa, which helps to maintain the mucosal barrier and protect the stomach lining from damage. Rebamipide may enhance the secretion of prostaglandin E2 and epidermal growth factor, which play important roles in promoting the healing of gastric ulcers and preventing their recurrence.
Rebamipide (CAS 90098-04-7) References
- Synthesis and antiulcer activity of optical isomers of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid (rebamipide). | Otsubo, K., et al. 1991. Chem Pharm Bull (Tokyo). 39: 2906-9. PMID: 1666022
- Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution. | Takagi, T., et al. 2011. World J Gastroenterol. 17: 3802-9. PMID: 21987622
- Rebamipide suppresses mite-induced asthmatic responses in NC/Nga mice. | Murakami, I., et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L872-8. PMID: 26472814
- Rebamipide ameliorates atherosclerosis by controlling lipid metabolism and inflammation. | Jhun, J., et al. 2017. PLoS One. 12: e0171674. PMID: 28241014
- Rebamipide ameliorates radiation-induced intestinal injury in a mouse model. | Shim, S., et al. 2017. Toxicol Appl Pharmacol. 329: 40-47. PMID: 28526636
- Rebamipide suppresses TNF-α production and macrophage infiltration in the conjunctiva. | Tajima, K., et al. 2018. Vet Ophthalmol. 21: 347-352. PMID: 29251403
- Intra-articular injection of rebamipide prevents articular cartilage degeneration in murine post-traumatic osteoarthritis models. | Suzuki, Y., et al. 2020. Mod Rheumatol. 30: 765-772. PMID: 31339809
- Reactions of Rebamipide with Hypobromous Acid. | Suzuki, T. and Okuyama, A. 2019. Chem Pharm Bull (Tokyo). 67: 1164-1167. PMID: 31582637
- [Rebamipide using in gastroesophageal reflux disease treatment]. | Ivashkin, VT., et al. 2020. Ter Arkh. 92: 98-104. PMID: 32598706
- Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota. | Tanigawa, T., et al. 2021. PLoS One. 16: e0245995. PMID: 33507971
- [Rebamipide: evidence base for use in gastroenterology]. | Andreev, DN. and Maev, IV. 2020. Ter Arkh. 92: 97-104. PMID: 33720581
- Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER. | Imai, T., et al. 2022. Sci Rep. 12: 2631. PMID: 35173236
- Rebamipide attenuates alcohol-induced gastric epithelial cell injury by inhibiting endoplasmic reticulum stress and activating autophagy-related proteins. | He, Q., et al. 2022. Eur J Pharmacol. 922: 174891. PMID: 35288192
- Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes. | Jhun, J., et al. 2022. PLoS One. 17: e0277692. PMID: 36574392
- In vitro studies indicating antioxidative properties of rebamipide. | Iinuma, S., et al. 1998. Dig Dis Sci. 43: 35S-39S. PMID: 9753224
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rebamipide, 1 g | sc-205835 | 1 g | $60.00 | |||
Rebamipide, 5 g | sc-205835A | 5 g | $204.00 |