RD3 Antibody (B-8): sc-376516
- RD3 Antibody (B-8) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 145-175 within an internal region of RD3 of human origin
- recommended for detection of RD3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for RD3 Antibody (B-8) for WB applications. These reagents are now offered in bundles with RD3 Antibody (B-8) (see ordering information below).
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RD3 Antibody (B-8) is a mouse monoclonal IgG1 antibody that detects RD3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RD3, also known as retinal degeneration 3 or LCA12, is a crucial 195 amino acid protein predominantly expressed in the retina, where RD3 plays a significant role in forming subnuclear protein complexes essential for various cellular processes, including transcription and splicing. Proper functioning of RD3 is vital for maintaining photoreceptor health and function; defects in RD3 lead to Leber congenital amaurosis type 12, a severe condition characterized by minimal or absent retinal photoreceptor activity in affected infants. This impairment underscores RD3′s importance in visual development and highlights anti-RD3 antibody (B-8) as a valuable tool for studying molecular mechanisms underlying retinal diseases and exploring therapeutic avenues in hereditary blindness.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RD3 Antibody (B-8) | sc-376516 | 200 µg/ml | $322.00 | |||
RD3 Antibody (B-8): m-IgG Fc BP-HRP Bundle | sc-540588 | 200 µg Ab; 10 µg BP | $361.00 | |||
RD3 Antibody (B-8): m-IgG1 BP-HRP Bundle | sc-542224 | 200 µg Ab; 20 µg BP | $361.00 | |||
RD3 (B-8) Neutralizing Peptide | sc-376516 P | 100 µg/0.5 ml | $69.00 |