RD Whole Cell Lysate: sc-364791

RD whole cell lysate is derived from the RD cell line, a human rhabdomyosarcoma line that is extensively used in myogenic and cancer research. This lysate provides a crucial resource for investigating the molecular and cellular mechanisms of muscle differentiation and the pathogenesis of muscle-derived tumors. RD lysate is particularly useful for studying the disruption of myogenic regulatory factors (MRFs), which are critical for muscle cell differentiation and are often dysregulated in rhabdomyosarcoma. Researchers utilize this lysate to examine the pathways that influence the cell cycle, apoptosis, and metastatic potential in muscle cells, including those mediated by MyoD, myogenin, and Pax7. It also facilitates the study of signaling cascades such as the Ras/MAPK and PI3K/Akt pathways, which are pivotal in cell growth and survival. Furthermore, RD cell lysate is instrumental in assessing the efficacy of various chemical agents that modulate these pathways in a research setting, providing insights into the cellular responses to genetic and environmental perturbations. This approach allows for a deeper understanding of rhabdomyosarcoma biology strictly within the confines of basic scientific inquiry, thereby enriching the foundational knowledge in myogenic research and oncology.