RBQ-3 Antibody (A-8): sc-374481
- RBQ-3 Antibody (A-8) is a mouse monoclonal IgG1 provided at 200 µg/ml
- specific for an epitope mapping between amino acids 445-481 within an internal region of RBQ-3 of human origin
- recommended for detection of RBQ-3 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG1 BP-HRP is the preferred secondary detection reagent for RBQ-3 Antibody (A-8) for WB applications. This reagent is now offered in a bundle with RBQ-3 Antibody (A-8) (see ordering information below).
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SEE ALSO...
RBQ-3 (A-8) is a mouse monoclonal IgG1 antibody. WD-repeats are motifs found in various proteins, characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins containing WD-repeats participate in diverse cellular functions, these proteins generally involve regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis, and vesicular trafficking. RBQ-3, also known as RBBP5 (retinoblastoma binding protein 5) or SWD1, is a 538 amino acid protein that localizes to the nucleus and contains six WD repeats. RBQ-3 functions as a component of the Set1 complex and preferentially binds to underphosphorylated forms of the retinoblastoma (Rb) protein, possibly playing a role in cell proliferation regulation. RBQ-3 exists as two alternatively spliced isoforms and, upon DNA damage, undergoes phosphorylation by ATM or ATR.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RBQ-3 Antibody (A-8) | sc-374481 | 200 µg/ml | $322.00 | |||
RBQ-3 Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-542700 | 200 µg Ab; 20 µg BP | $361.00 | |||
RBQ-3 (A-8) Neutralizing Peptide | sc-374481 P | 100 µg/0.5 ml | $69.00 |