RAW 309 Cr.1 Cell Lysate: sc-3814

RAW 309 Cr.1 cell lysate is derived from the RAW 309 Cr.1 cell line, a murine macrophage line widely used in immunology and inflammation research. This lysate is instrumental in studying macrophage activation, signaling pathways, and the immune responses associated with inflammation. Researchers use RAW 309 Cr.1 lysate to explore the intracellular processes triggered by various immunological stimuli, such as lipopolysaccharide (LPS), which is known to activate toll-like receptor 4 (TLR4) and induce a potent inflammatory response. This cell line is particularly valuable for examining the NF-κB signaling pathway, which plays a crucial role in the transcriptional activation of genes involved in immune response and inflammation. Additionally, the lysate allows for the investigation of cytokine production, phagocytic activity, and the expression of surface molecules critical for macrophage function. By using RAW 309 Cr.1 cell lysate, scientists gain insights into the mechanisms of macrophage-mediated immunity and the cellular responses to pathogens and inflammatory signals. This research contributes to a fundamental understanding of macrophage biology, thereby enriching the basic scientific knowledge of immune system dynamics.