rat thyroid extract: sc-2402
- 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
- Western blotting positive control
- recommended use is 50 µg (20 µl) per lane
- extracts should be stored at -20°C and repeated freezing and thawing should be minimized
- sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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Rat thyroid extract is a biological preparation derived from the thyroid glands of rats. It contains a complex mixture of thyroid hormones, including thyroxine (T4) and triiodothyronine (T3), along with various proteins and other bioactive molecules naturally present in the thyroid tissue. The extract is commonly used in scientific research to study thyroid physiology, hormone signaling pathways, and thyroid-related diseases. Researchers utilize rat thyroid extract in cell culture experiments to investigate the effects of thyroid hormones on cellular processes such as metabolism, growth, and differentiation. Additionally, it is employed in in vitro assays to examine thyroid hormone receptor binding, gene expression regulation, and downstream signaling events. Rat thyroid extract has also been utilized in animal studies to induce experimental hyperthyroidism or hypothyroidism in rodent models, allowing researchers to investigate the physiological and pathological consequences of thyroid hormone dysregulation. Overall, rat thyroid extract serves as a valuable research tool for elucidating the mechanisms of thyroid hormone action and exploring potential strategies for thyroid disorders.
rat thyroid extract References:
- 5-Hydroxytryptamine in mammalian thyroid gland. | PAASONEN, MK. 1958. Experientia. 14: 95-6. PMID: 13537886
- Fat metabolism in experimental obesities. VIII. Blood total lipids and ketones in four kinds of obese mice. | MAYER, J. and SILIDES, DJ. 1958. Experientia. 14: 96-9. PMID: 13537887
- THYROID HYPOCALCEMIC PRINCIPLE AND RECURRENT LARYNGEAL NERVE INJURY AS FACTORS AFFECTING THE RESPONSE TO PARATHYROIDECTOMY IN RATS. | HIRSCH, PF., et al. 1963. Endocrinology. 73: 244-52. PMID: 14076205
- A STUDY OF THE THYROID PROTEIN METABOLISM OF THE THIOURACIL-TREATED RAT. | PERELMUTTER, L., et al. 1965. Can J Biochem. 43: 399-405. PMID: 14329907
- Studies on a cyclic AMP-dependent protein kinase from rat thyroid gland. | Leonard, JL. and Rosenberg, LL. 1977. Biochim Biophys Acta. 484: 336-47. PMID: 199261
- Transfer of experimental autoimmune thyroiditis with T cell clones. | Romball, CG. and Weigle, WO. 1987. J Immunol. 138: 1092-8. PMID: 2433339
- Prevention of autoimmune thyroiditis in T cell-depleted rats by injections of crude thyroid extract. | Whitmore, DB. and Irvine, WJ. 1977. Clin Exp Immunol. 29: 474-9. PMID: 303967
- Hormonal regulation of DNA polymerase-beta activity in the rat thyroid gland. | Nagasaka, A., et al. 1988. J Endocrinol. 119: 303-8. PMID: 3199062
- Spontaneous and methylcholanthrene-enhanced thyroiditis in BUF rats. II. Induction of experimental autoimmune thyroiditis without completed Freund′s adjuvant. | Silverman, D. and Rose, NR. 1975. J Immunol. 114: 148-50. PMID: 46238
- Antibodies to porcine thyrocalcitonin: effects on the hypocalcemic activity of calf, rat and monkey thyroid extracts. | Tashjian, AH. and Munson, PL. 1965. Endocrinology. 77: 520-8. PMID: 4953875
- The production of thyroid autoantibodies in mice. | Twarog, FJ. and Rose, NR. 1968. J Immunol. 101: 242-50. PMID: 5668024
- The adjuvant effect of pertussis vaccine in experimental thyroiditis of the rat. | Twarog, FJ. and Rose, NR. 1969. Proc Soc Exp Biol Med. 130: 434-9. PMID: 5765278
- The activity of different fractions of homologous thyroid extract in the production of allergic thyroiditis in the rat. | Roitt, IM., et al. 1965. Immunology. 9: 281-6. PMID: 5838199
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
rat thyroid extract | sc-2402 | 500 µg/200 µl | $120.00 |