Date published: 2026-5-6

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rat lung extract: sc-2396

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Datasheets
  • 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
  • Western blotting positive control
  • recommended use is 50 µg (20 µl) per lane
  • extracts should be stored at -20°C and repeated freezing and thawing should be minimized
  • sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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Rat lung extract is a biochemical preparation obtained from the lung tissue of rats, containing a complex mixture of proteins, enzymes, and other biologically active molecules native to pulmonary tissue. The extract is commonly used in scientific research to investigate various aspects of lung physiology and pathology. Researchers utilize rat lung extract to study respiratory functions such as gas exchange, lung development, and pulmonary surfactant production. Additionally, it serves as a valuable tool for examining mechanisms underlying respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis. Studies employing rat lung extract have explaind molecular pathways involved in inflammation, oxidative stress, and tissue remodeling in the lung, providing insights into disease pathogenesis and potential targets. Furthermore, researchers utilize this extract in cell culture experiments to explore the effects of lung-derived factors on cellular processes such as proliferation, differentiation, and apoptosis. Overall, rat lung extract plays a crucial role in advancing our understanding of lung biology and disease mechanisms, facilitating the development of novel strategies for the diagnosis and treatment of respiratory disorders.

rat lung extract References:

  1. A region in the 3′ UTR of MnSOD RNA enhances translation of a heterologous RNA.  |  Knirsch, L. and Clerch, LB. 2000. Biochem Biophys Res Commun. 272: 164-8. PMID: 10872821
  2. Tyrosine phosphorylation regulates manganese superoxide dismutase (MnSOD) RNA-binding protein activity and MnSOD protein expression.  |  Knirsch, L. and Clerch, LB. 2001. Biochemistry. 40: 7890-5. PMID: 11425317
  3. The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site.  |  Ishihara, K., et al. 2003. FEBS Lett. 550: 107-13. PMID: 12935895
  4. Lectin KM+-induced neutrophil haptotaxis involves binding to laminin.  |  Ganiko, L., et al. 2005. Biochim Biophys Acta. 1721: 152-63. PMID: 15652190
  5. Lung contains an inhibitor for nicotinatemononucleotide pyrophosphorylase (carboxylating) of NAD biosynthesis.  |  Seither, RL., et al. 1991. Life Sci. 48: 253-9. PMID: 1992282
  6. Enhancement of colony forming ability in the lung by transfer of the v-fos oncogene into a ras-transformed rat 3Y1 cell line.  |  Nakamatsu, K., et al. 1989. FEBS Lett. 257: 422-6. PMID: 2511041
  7. Partial purification of a binding protein for polychlorinated biphenyls from rat lung cytosol: physicochemical and immunochemical characterization.  |  Lund, J., et al. 1988. Biochemistry. 27: 7895-901. PMID: 3145015
  8. Measurement of beta-carbolines by high-performance liquid chromatography with fluorescence detection.  |  Bosin, TR. and Faull, KF. 1988. J Chromatogr. 428: 229-36. PMID: 3215926
  9. Analysis of 6-keto PGF1 alpha, 5-HETE, and LTC4 in rat lung: comparison of GM/MS, RIA, and EIA.  |  Westcott, JY., et al. 1986. Prostaglandins. 32: 857-73. PMID: 3550900
  10. Aminopeptidase P activity in rat organs and human serum.  |  Holtzman, EJ., et al. 1987. Anal Biochem. 162: 476-84. PMID: 3605610
  11. Pulmonary bombesin in experimentally induced asbestosis in rats.  |  Day, R., et al. 1985. Exp Lung Res. 8: 1-13. PMID: 3996331
  12. Asbestos-related increase in pulmonary levels of vasoactive intestinal peptide (VIP).  |  Day, R., et al. 1983. Life Sci. 33: 1869-76. PMID: 6196589
  13. A 3′ untranslated region of catalase mRNA composed of a stem-loop and dinucleotide repeat elements binds a 69-kDa redox-sensitive protein.  |  Clerch, LB. 1995. Arch Biochem Biophys. 317: 267-74. PMID: 7872794
  14. Rat lung contains a developmentally regulated manganese superoxide dismutase mRNA-binding protein.  |  Fazzone, H., et al. 1993. J Clin Invest. 92: 1278-81. PMID: 8376586
  15. Early divergent lung antioxidant enzyme expression in response to lipopolysaccharide.  |  Clerch, LB., et al. 1996. Am J Physiol. 271: L949-54. PMID: 8997265

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

rat lung extract

sc-2396
500 µg/200 µl
$120.00