Date published: 2026-5-6

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rat kidney extract: sc-2394

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Datasheets
  • 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
  • Western blotting positive control
  • recommended use is 50 µg (20 µl) per lane
  • extracts should be stored at -20°C and repeated freezing and thawing should be minimized
  • sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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Rat kidney extract, derived from the renal tissue of rats, serves as a valuable research tool in studying kidney physiology and related diseases. This extract contains a diverse array of proteins, enzymes, and signaling molecules native to renal cells, enabling researchers to explore various aspects of kidney function. Mechanistically, rat kidney extract has been employed to investigate processes such as filtration, reabsorption, and secretion within the nephron, shedding light on fundamental mechanisms underlying kidney homeostasis and regulation of electrolyte and water balance. Additionally, researchers utilize this extract to study renal pathologies including acute kidney injury, chronic kidney disease, and renal fibrosis. By examining the molecular pathways involved in these conditions, studies employing rat kidney extract have contributed to the identification of potential targets and the development of novel treatment strategies. Furthermore, this extract is utilized in cell culture experiments to simulate the renal microenvironment and study the effects of kidney-derived factors on cellular behavior, such as proliferation, migration, and differentiation. Overall, rat kidney extract plays a crucial role in advancing our understanding of kidney biology and pathology, offering insights that may lead to improved diagnostic methods and interventions for kidney diseases.

rat kidney extract References:

  1. Rat renal and plasma prorenin are activated in vitro by different mechanisms.  |  Vincent, PA. and De Vito, E. 1999. Hypertension. 34: 520-4. PMID: 10489404
  2. Differences in the enzymatic inactivation of arginine vasopressin and oxytocin by rat kidney homogenate.  |  Walter, R. and Shlank, H. 1975. Endocrinology. 96: 811-4. PMID: 1116488
  3. Substrate inhibition of rat liver and kidney arginase with fluoride.  |  Tormanen, CD. 2003. J Inorg Biochem. 93: 243-6. PMID: 12576287
  4. Production of nephrotic syndrome in rats by Freund′s adjuvants and rat kidney suspensions.  |  HEYMANN, W., et al. 1959. Proc Soc Exp Biol Med. 100: 660-4. PMID: 13645677
  5. Inhibition of tritiated thymidine incorporation in cultured cells by rat kidney extract.  |  Klein, K., et al. 1979. J Natl Cancer Inst. 62: 1557-64. PMID: 155753
  6. Oleamide synthesizing activity from rat kidney: identification as cytochrome c.  |  Driscoll, WJ., et al. 2007. J Biol Chem. 282: 22353-63. PMID: 17496328
  7. Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.  |  Bilgin, M., et al. 2016. Sci Rep. 6: 27920. PMID: 27312775
  8. Application of immunochemical methods to the identification and characterization of rat kidney inactive renin.  |  Takii, Y., et al. 1985. Hypertension. 7: 236-43. PMID: 3884504
  9. Experimental glomerulonephritis induced with the major antigen of rat kidney.  |  Dinh, BL., et al. 1972. Int Arch Allergy Appl Immunol. 43: 131-44. PMID: 4120032
  10. Stimulation of cell division in larval kidney (Xenopus laevis) by rat kidney antiserum.  |  Chopra, DP. and Simnett, JD. 1971. Exp Cell Res. 64: 396-402. PMID: 4250774
  11. Renin content in subcellular fractions of normal rat kidney extract.  |  Onoyama, K., et al. 1973. Jpn Heart J. 14: 440-4. PMID: 4357687
  12. Preliminary communication on the discrepancy between renin activity and hypertension-inducing potency in rat kidney extract dual renal pressor substance hypothesis.  |  Kira, J., et al. 1971. Jpn Circ J. 35: 1591-3. PMID: 5172478
  13. Studies on the native forms of renin in the rat kidney.  |  Rubin, I., et al. 1980. Biochim Biophys Acta. 612: 126-36. PMID: 6988009
  14. Synthesis of a di-O-methylated pentasaccharide for use in the assay of N-acetylglucosaminyltransferase III activity.  |  Khan, SH., et al. 1994. Carbohydr Res. 262: 283-95. PMID: 7982220
  15. Mouse and rat plasma renin concentration and gene expression in (mRen2)27 transgenic rats.  |  Bohlender, J., et al. 1998. Am J Physiol. 274: H1450-6. PMID: 9612349

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

rat kidney extract

sc-2394
500 µg/200 µl
$120.00