Molecular structure of Ramiprilat-d5 Acyl-β-D-glucuronide
Ramiprilat-d5 Acyl-β-D-glucuronide
Application:
Ramiprilat-d5 Acyl-β-D-glucuronide is a labeled metabolite of Ramipril
Molecular Weight:
569.61
Molecular Formula:
C27H31D5N2O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ramiprilat-d5 Acyl-β-D-glucuronide is a labeled metabolite of Ramipril (sc-205833). Ramipril is an inhibitor of the angiotensin-coverting enzyme (ACE) that is reported to quickly hydrolyze into the active metabolite Ramiprilat, after absorption. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril (sc-208496). Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18.
Ramiprilat-d5 Acyl-β-D-glucuronide References
- Spotlight on ramipril in the prevention of cardiovascular outcomes. | Warner, GT. and Perry, CM. 2003. Am J Cardiovasc Drugs. 3: 113-6. PMID: 14727938
- Effects of ramipril on serum monocyte chemoattractant protein 1, interleukin-18, and interleukin-10 in elderly patients with acute coronary syndrome. | Chen, HQ., et al. 2010. Heart Vessels. 25: 77-81. PMID: 20339966
- Differences between zofenopril and ramipril, two ACE inhibitors, on cough induced by citric acid in guinea pigs: role of bradykinin and PGE2. | Cialdai, C., et al. 2010. Naunyn Schmiedebergs Arch Pharmacol. 382: 455-61. PMID: 20848272
Inhibitor of:
ACE.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ramiprilat-d5 Acyl-β-D-glucuronide, 1 mg | sc-219947 | 1 mg | $4500.00 |