BRAF Antibody (13): sc-136263
- BRAF Antibody (13) is a mouse monoclonal IgG2a, cited in 2 publications, provided at 50 µg/0.5 ml
- raised against amino acids 285-406 of Raf-B of human origin
- recommended for detection of Raf-B of mouse, rat and human origin by WBIP
- See BRAF (F-7): sc-5284 for BRAF antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BRAF Antibody (13). This work is in progress.
Raf-B Antibody (13) is a mouse monoclonal IgG2a antibody that detects Raf-B in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Raf-B is a member of the Raf gene family of serine/threonine protein kinases, which play a crucial role in the regulation of cell signaling pathways that control various cellular processes, including growth, differentiation, and survival. Raf-B is primarily located in the cytoplasm, where anti-Raf-B antibody (13) identifies this key mediator in the mitogen-activated protein kinase (MAPK) signaling cascade, influencing cellular responses to growth factors and stress signals. Understanding Raf-B localization is important because cellular activity can be modulated by various upstream signals, and misregulation has been implicated in several diseases, including cancer. Raf-B exhibits a high degree of homology with Raf-1, particularly within the kinase domain, suggesting shared regulatory mechanisms and functional roles in cellular signaling. Raf-B (13) monoclonal antibody serves as an essential tool for researchers studying the intricate signaling networks that govern cell behavior and potential therapeutic targets within these pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BRAF Antibody (13) | sc-136263 | 50 µg/0.5 ml | $322.00 |