Rad17 Antibody (6A173): sc-71951
- Rad17 Antibody (6A173) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against a Rad17 fusion protein of S. pombe origin
- recommended for detection of Rad17 of y origin by WB
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Rad17 Antibody (6A173) for WB applications. These reagents are now offered in bundles with Rad17 Antibody (6A173) (see ordering information below).
Rad17 Antibody (6A173) is a mouse monoclonal IgG1 antibody that detects Rad17 in yeast by western blotting (WB). Rad17 plays a crucial role in the DNA damage response, particularly in the activation of the G1 and G2 checkpoints, which are essential for maintaining genomic integrity. Rad17 is located at DNA damage sites, where Rad17 acts as a sensor that helps initiate the repair process, thereby preventing damaged DNA replication. Proper functioning of Rad17 ensures cells do not proceed through the cell cycle with unrepaired DNA, which could lead to mutations and potentially cancerous transformations. Additionally, Rad17 interacts with other checkpoint proteins, such as Rad9 and Mec3, to form a complex that is critical for the signaling cascade that activates cell cycle arrest in response to DNA damage. Using anti-Rad17 antibody (6A173) in research can provide valuable insights into DNA repair mechanisms and cell cycle checkpoint regulation, contributing to a better understanding of cellular responses to genotoxic stress.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rad17 Antibody (6A173) | sc-71951 | 200 µg/ml | $322.00 | |||
Rad17 Antibody (6A173): m-IgG Fc BP-HRP Bundle | sc-539432 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rad17 Antibody (6A173): m-IgG1 BP-HRP Bundle | sc-541483 | 200 µg Ab; 20 µg BP | $361.00 |