Date published: 2026-1-1

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rac threo-Dihydrobupropion (CAS 92264-82-9)

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Alternate Names:
(R*,R*)-3-Chloro-alpha-[1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol
Application:
rac threo-Dihydrobupropion is a metabolite of the drug Bupropion
CAS Number:
92264-82-9
Molecular Weight:
241.76
Molecular Formula:
C13H20ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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rac threo-Dihydrobupropion is an important chiral compound utilized extensively in the field of psychopharmacology research. The focus on its enantiomers, or optical isomers, offers researchers a deeper understanding of the relationship between molecular chirality and mechanism of action. Studies typically explore how each enantiomer interacts with neurotransmitter systems, providing insights into the mechanisms underlying synaptic transmission. In analytical chemistry, rac threo-Dihydrobupropion serves as a reference compound in chiral chromatography, aiding in the development of more precise separation techniques for complex mixtures of stereoisomers. Additionally, its role as an intermediate in synthetic chemistry is investigated to enhance the efficiency of stereoselective synthesis, which is for producing enantiomerically pure substances needed for high-fidelity research applications.


rac threo-Dihydrobupropion (CAS 92264-82-9) References

  1. Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS.  |  Masters, AR., et al. 2016. J Chromatogr B Analyt Technol Biomed Life Sci. 1015-1016: 201-208. PMID: 26946423
  2. Fall Creek Monitoring Station: Highly Resolved Temporal Sampling to Prioritize the Identification of Nontarget Micropollutants in a Small Stream.  |  Carpenter, CMG., et al. 2019. Environ Sci Technol. 53: 77-87. PMID: 30472836

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

rac threo-Dihydrobupropion, 10 mg

sc-219886
10 mg
$317.00