rac-Ruxolitinib-d9 (Major) (CAS 941688-05-7 (unlabeled))

Rac-Ruxolitinib-d9 (Major) is a deuterated analog of rac-Ruxolitinib, specifically designed for use in analytical and biochemical research. This compound incorporates deuterium atoms, replacing hydrogen, to create a version with a slightly higher molecular weight, which is a critical feature in mass spectrometry and NMR spectroscopy studies. This modification does not significantly alter the chemical or biological properties of the molecule but provides an invaluable tool for tracing the metabolic pathways and distribution of rac-Ruxolitinib in various biological systems. By facilitating the precise quantification and differentiation from its non-deuterated counterpart, rac-Ruxolitinib-d9 (Major) serves as an essential standard in pharmacokinetic studies, enabling researchers to dissect the intricate mechanisms by which rac-Ruxolitinib interacts with cellular targets, primarily focusing on its role in modulating signal transduction pathways involved in cellular growth and proliferation. This, in turn, aids in the elucidation of the fundamental biological processes underlying various conditions at the molecular level, contributing significantly to the advancement of biochemical research.