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rac Methotrimeprazine Hydrochloride (CAS 4185-80-2)

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Application:
rac Methotrimeprazine Hydrochloride is a phenothiazine compound
CAS Number:
4185-80-2
Molecular Weight:
364.93
Molecular Formula:
C19H25ClN2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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rac Methotrimeprazine Hydrochloride is a racemic preparation of the phenothiazine compound Methotrimeprazine. The compound Methotrimeprazine contains a stereodefined methyl group on the propanamine side chain, and rac Methotrimeprazine Hydrochloride is racemitized at that position. rac Methotrimeprazine Hydrochloride may serve as a useful sample for studying Methotrimeprazine action and metabolism.


rac Methotrimeprazine Hydrochloride (CAS 4185-80-2) References

  1. Determination of methotrimeprazine in pharmaceutical preparations by visible spectrophotometry.  |  Kedor-Hackmann, ER., et al. 2000. Drug Dev Ind Pharm. 26: 261-6. PMID: 10738643
  2. Antipsychotic-related QTc prolongation, torsade de pointes and sudden death.  |  Haddad, PM. and Anderson, IM. 2002. Drugs. 62: 1649-71. PMID: 12109926
  3. Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels.  |  Chiu, PJ., et al. 2004. J Pharmacol Sci. 95: 311-9. PMID: 15272206
  4. Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp.  |  Dubin, AE., et al. 2005. J Biomol Screen. 10: 168-81. PMID: 15799960
  5. Serotonin syndrome after concomitant treatment with linezolid and meperidine.  |  Das, PK., et al. 2008. Clin Infect Dis. 46: 264-5. PMID: 18171260
  6. Sodium chloride equivalents, cryoscopic properties, and hemolytic effects of certain medicinals in aqueous solution. V: Supplemental values.  |  Hammarlund, ER. 1989. J Pharm Sci. 78: 519-20. PMID: 2760830
  7. A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions.  |  Keary, EM. and Maxwell, DR. 1967. Br J Pharmacol Chemother. 30: 400-16. PMID: 6036418
  8. Rapid spectrophotometric assay of phenothiazine drugs in pharmaceutical preparations.  |  Taha, AM., et al. 1983. Analyst. 108: 1500-5. PMID: 6142664
  9. Impact of biological matrix and isolation methods on detectability and interlaboratory variations of TLC Rf-values in systematic toxicological analysis.  |  Bogusz, M., et al. 1984. J Anal Toxicol. 8: 149-54. PMID: 6471812
  10. Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion.  |  van Heijst, AN., et al. 1983. J Toxicol Clin Toxicol. 20: 307-18. PMID: 6655772

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

rac Methotrimeprazine Hydrochloride, 10 mg

sc-212732
10 mg
$300.00