rac Efavirenz-d4 (CAS 1246812-58-7)
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Rac Efavirenz-d4 is a derivative of efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used in laboratory research to investigate the intricate molecular mechanisms underlying HIV-1 replication. The application of rac Efavirenz-d4 extends into kinetic research, where it can be used to investigate the dynamics of efavirenz metabolism. By tracking the deuterium-labeled compound, researchers can gain insights into how efavirenz is processed within biological systems, including its absorption, distribution, metabolic pathways, and elimination. Moreover, the use of a racemic mixture containing both enantiomers of efavirenz-d4 allows for a comprehensive understanding of the molecule′s behavior in stereochemical terms.
rac Efavirenz-d4 (CAS 1246812-58-7) References
- Predictors of Efavirenz Plasma Exposure, Auto-Induction Profile, and Effect of Pharmacogenetic Variations among HIV-Infected Children in Ethiopia: A Prospective Cohort Study. | Chala, A., et al. 2021. J Pers Med. 11: PMID: 34945777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
rac Efavirenz-d4, 1 mg | sc-497385 | 1 mg | $765.00 |