Molecular structure of rac Demethyl Citalopram Hydrochloride, CAS Number: 97743-99-2
rac Demethyl Citalopram Hydrochloride (CAS 97743-99-2)
Alternate Names:
1-(4-Fluorophenyl)-1,3-dihydro-1-(3-(methylamino)propyl)isobenzofuran-5-carbonitrile
Application:
rac Demethyl Citalopram Hydrochloride is a metabolite of Citalopram and potential 5-HT inhibitor
CAS Number:
97743-99-2
Molecular Weight:
346.83
Molecular Formula:
C19H19FN2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
rac Demethyl Citalopram Hydrochloride is a metabolite of Citalopram (sc-201123). Citalopram is a selective inhibitor of the ST (5-hydroxytryptamine transporter, serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.
rac Demethyl Citalopram Hydrochloride (CAS 97743-99-2) References
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
- Process design for removal of pharmaceuticals in wastewater treatment plants based on predicted no effect concentration (PNEC) | Kisielius, V., Kharel, S., Skaarup, J., Lauritzen, B. S., Lukas, M., Bogusz, A.,.. & Bester, K. 2023. Chemical Engineering Journal. 476: 146644.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
rac Demethyl Citalopram Hydrochloride, 1 mg | sc-208273 | 1 mg | $290.00 |